A combination of provirus stimulants with blockers of regulators of complement activation represents a novel approach for purging HIV-1 latently infected cells

被引：0
|
作者：
Lan, Jie [1 ,2 ]
Byrd, Daniel [1 ,2 ]
Amet, Tohti [1 ,2 ]
Yu, Qigui [1 ,2 ,3 ]
机构：
[1] Indiana Univ, Sch Med, Ctr AIDS Res, Indianapolis, IN USA
[2] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
[3] Indiana Univ, Sch Med, Div Infect Dis, Indianapolis, IN USA
来源：
JOURNAL OF IMMUNOLOGY | 2013年 / 190卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
P6342
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
    Promsote, Wanwisa
    Xu, Ling
    Hataye, Jason
    Fabozzi, Giulia
    March, Kylie
    Almasri, Cassandra G.
    DeMouth, Megan E.
    Lovelace, Sarah E.
    Talana, Chloe Adrienna
    Doria-Rose, Nicole A.
    McKee, Krisha
    Hait, Sabrina Helmold
    Casazza, Joseph P.
    Ambrozak, David
    Beninga, Jochen
    Rao, Ercole
    Furtmann, Norbert
    Birkenfeld, Joerg
    McCarthy, Elizabeth
    Todd, John-Paul
    Petrovas, Constantinos
    Connors, Mark
    Hebert, Andrew T.
    Beck, Jeremy
    Shen, Junqing
    Zhang, Bailin
    Levit, Mikhail
    Wei, Ronnie R.
    Yang, Zhi-yong
    Pegu, Amarendra
    Mascola, John R.
    Nabel, Gary J.
    Koup, Richard A.
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [42] Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
    Wanwisa Promsote
    Ling Xu
    Jason Hataye
    Giulia Fabozzi
    Kylie March
    Cassandra G. Almasri
    Megan E. DeMouth
    Sarah E. Lovelace
    Chloe Adrienna Talana
    Nicole A. Doria-Rose
    Krisha McKee
    Sabrina Helmold Hait
    Joseph P. Casazza
    David Ambrozak
    Jochen Beninga
    Ercole Rao
    Norbert Furtmann
    Joerg Birkenfeld
    Elizabeth McCarthy
    John-Paul Todd
    Constantinos Petrovas
    Mark Connors
    Andrew T. Hebert
    Jeremy Beck
    Junqing Shen
    Bailin Zhang
    Mikhail Levit
    Ronnie R. Wei
    Zhi-yong Yang
    Amarendra Pegu
    John R. Mascola
    Gary J. Nabel
    Richard A. Koup
    Nature Communications, 14
  • [43] Transfer of HIV-1 from HIV-1 latently infected CD34+ haematopoietic progenitors to CD4+ T cells
    Cheung, A. K. L.
    Huang, Y.
    Chen, M.
    Chen, Z. W.
    HONG KONG MEDICAL JOURNAL, 2019, 25 (05) : 37 - 40
  • [44] Galectin-3 is involved in HIV-1 expression through NF-κB activation and associated with Tat in latently infected cells
    Okamoto, Mika
    Hidaka, Akemi
    Toyama, Masaaki
    Baba, Masanori
    VIRUS RESEARCH, 2019, 260 : 86 - 93
  • [45] Blockage of CD59 Function Restores Activities of Neutralizing and Nonneutralizing Antibodies in Triggering Antibody-Dependent Complement-Mediated Lysis of HIV-1 Virions and Provirus-Activated Latently Infected Cells
    Yang, Kai
    Lan, Jie
    Shepherd, Nicole
    Hu, Ningjie
    Xing, Yanyan
    Byrd, Daniel
    Amet, Tohti
    Jewell, Corlin
    Gupta, Samir
    Kounga, Carole
    Gao, Jimin
    Yu, Qigui
    JOURNAL OF VIROLOGY, 2015, 89 (18) : 9393 - 9406
  • [46] Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells
    Carlin, Eric
    Greer, Braxton
    Lowman, Kelsey
    Duverger, Alexandra
    Wagner, Frederic
    Moylan, David
    Dalecki, Alexander
    Samuel, Shekwonya
    Perez, Mildred
    Sabbaj, Steffanie
    Kutsch, Olaf
    PLOS PATHOGENS, 2021, 17 (01)
  • [47] Histonedeacetylase inhibitor Oxamflatin increase HIV-1 transcription by inducing histone modification in latently infected cells
    Yin, Hao
    Zhang, Yuhao
    Zhou, Xin
    Zhu, Huanzhang
    MOLECULAR BIOLOGY REPORTS, 2011, 38 (08) : 5071 - 5078
  • [48] T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin
    Lindqvist, Birgitta
    Jutte, Bianca B.
    Love, Luca
    Assi, Wlaa
    Roux, Julie
    Sonnerborg, Anders
    Tezil, Tugsan
    Verdin, Eric
    Svensson, J. Peter
    PLOS PATHOGENS, 2022, 18 (06)
  • [49] The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells
    Pan, Hanyu
    Lu, Panpan
    Shen, Yinzhong
    Wang, Yanan
    Jiang, Zhengtao
    Yang, Xinyi
    Zhong, Yangcheng
    Yang, He
    Khan, Inam Ulla
    Zhou, Muya
    Li, Bokang
    Zhang, Ziyu
    Xu, Jianqing
    Lu, Hongzhou
    Zhu, Huanzhang
    ONCOTARGET, 2017, 8 (55) : 94104 - 94116
  • [50] Stability and Hopf Bifurcation in an HIV-1 Infection Model with Latently Infected Cells and Delayed Immune Response
    Wang, Haibin
    Xu, Rui
    DISCRETE DYNAMICS IN NATURE AND SOCIETY, 2013, 2013
12345