Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials

被引：116

作者：

Vetvicka, Vaclav ^{[1
]}

Vannucci, Luca ^{[2
]}

Sima, Petr ^{[2
]}

Richter, Josef ^{[3
]}

机构：

[1] Univ Louisville, Dept Pathol & Lab Med, Louisville, KY 40292 USA

[2] Inst Microbiol, Dept Immunol, Prague 14220, Czech Republic

[3] Zdravotni Ustav Sidlem Usti Nad Labem, Usti Nad Labem 40001, Czech Republic

来源：

MOLECULES | 2019年 / 24卷 / 07期

关键词：

glucan; drug; immunity; food; supplement; infection; mushrooms; PLEUROTUS-OSTREATUS; INNATE IMMUNITY; RESPIRATORY-INFECTIONS; OAT-BRAN; RESISTANCE; RESPONSES; MICE; NUTRITION; CYTOKINES; ANTITUMOR;

D O I：

10.3390/molecules24071251

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glucans are part of a group of biologically active natural molecules and are steadily gaining strong attention not only as an important food supplement, but also as an immunostimulant and potential drug. This paper represents an up-to-date review of glucans (beta-1,3-glucans) and their role in various immune reactions and the treatment of cancer. With more than 80 clinical trials evaluating their biological effects, the question is not if glucans will move from food supplement to widely accepted drug, but how soon.

引用

页数：17

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