Development of an ultrahigh-resolution Si-PM-based dual-head GAGG coincidence imaging system

被引:11
|
作者
Yamamoto, Seiichi [1 ]
Watabe, Hiroshi [2 ]
Kanai, Yasukazu [2 ]
Kato, Katsuhiko
Hatazawa, Jun [2 ,3 ]
机构
[1] Nagoya Univ, Grad Sch Med, Dept Radiol & Med Lab Sci, Higashi Ku, Nagoya, Aichi 4618673, Japan
[2] Osaka Univ, Grad Sch Med, Dept Mol Imaging Med, Osaka, Japan
[3] Osaka Univ, Grad Sch Med, Dept Nucl Med & Tracer Kinet, Osaka, Japan
关键词
Si-PM; Coincidence; Imaging; Ultra high resolution; GAGG; PET; DETECTOR;
D O I
10.1016/j.nima.2012.11.098
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A silicon photomultiplier (Si-PM) is a promising photodetector for high resolution PET systems due to its small channel size and high gain. Using Si-PMs, it will be possible to develop a high resolution imaging systems. For this purpose, we developed a small field-of-view (FOV) ultrahigh-resolution Si-PM-based dual-head coincidence imaging system for small animals and plant research. A new scintillator, Ce doped Gd3Al12Ga3O12 (GAGG), was selected because of its high light output and its emission wavelength matched with the Si-PM arrays and contained no radioactivity. Each coincidence imaging block detector consists of 0.5 x 0.5 x 5 mm(3) GAGG pixels combined with a 0.1-mm thick reflector to form a 20 x 17 matrix that was optically coupled to a Si-PM array (Hamamatsu MPPC S11064-050P) with a 1.5-mm thick light guide. The GAGG block size was 12.0 x 10.2 mm(2). Two GAGG block detectors were positioned face to face and set on a flexible arm based detector stand. All 0.5 mm GAGG pixels in the block detectors were clearly resolved in the 2-dimensional position histogram. The energy resolution was 14.4% FWHM for the Cs-137 gamma ray. The spatial resolution was 0.7 mm FWHM measured using a 0.25 mm diameter Na-22 point source. Small animal and plant images were successfully obtained. We conclude that our developed ultrahigh-resolution Si-PM-based dual-head coincidence imaging system is promising for small animal and plant imaging research. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:183 / 189
页数:7
相关论文
共 28 条
  • [21] Imaging of lung cancer with fluorine-18 fluorodeoxyglucose: comparison of a dual-head gamma camera in coincidence mode with a full-ring positron emission tomography system
    W. A. Weber
    J. Neverve
    J. Sklarek
    S. I. Ziegler
    P. Bartenstein
    B. King
    T. Treumann
    A. Enterrottacher
    M. Krapf
    K. E. Häußinger
    H. Lichte
    H. W. Präuer
    O. Thetter
    M. Schwaiger
    European Journal of Nuclear Medicine, 1999, 26 : 388 - 395
  • [22] Imaging of lung cancer with fluorine-18 fluorodeoxyglucose:: comparison of a dual-head gamma camera in coincidence mode with a full-ring positron emission tomography system
    Weber, WA
    Neverve, J
    Sklarek, J
    Ziegler, SI
    Bartenstein, P
    King, B
    Treumann, T
    Enterrottacher, A
    Krapf, M
    Häussinger, KE
    Lichte, H
    Präuer, HW
    Thetter, O
    Schwaiger, M
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1999, 26 (04) : 388 - 395
  • [23] An ultrahigh spatial resolution radiation-imaging detector using 0.1 mm x 0.1 mm pixelated GAGG plate combined with 1 mm channel size Si-PM array
    Yamamoto, Seiichi
    Kataoka, Jun
    Kamada, Kei
    Yoshikawa, Akira
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2019, 919 : 125 - 133
  • [24] Development of an ultrahigh resolution 1 mm Si-PM array based GGAG alpha particle imaging detector with gamma or X-ray separation capability
    Yamamoto, Seiichi
    Kataoka, Jun
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2024, 1066
  • [25] Performance evaluation of a newly developed high-resolution, dual-head animal SPECT system based on the NEMA NU1-2007 standard
    Moji, Vahideh
    Zeraatkar, Navid
    Farahani, Mohammad Hossein
    Aghamiri, Mahmood Reza
    Sajedi, Salar
    Teimourian, Behnoosh
    Ghafarian, Pardis
    Sarkar, Saeed
    Ay, Mohammad Reza
    JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 2014, 15 (06): : 267 - 278
  • [26] The benefit of functional-anatomical imaging with [18F]fluorodeoxyglucose utilizing a dual-head coincidence gamma camera with an integrated X-ray transmission system in non-small cell lung cancer
    Eschmann, SM
    Bitzer, M
    Paulsen, F
    Friedel, G
    Besenfelder, H
    Horger, M
    Reimold, M
    Dittmann, H
    Pfannenberg, AC
    Bares, R
    NUCLEAR MEDICINE COMMUNICATIONS, 2004, 25 (09) : 909 - 915
  • [27] Development of a dual detector system based on a-Si:H arrays and multi-element silicon detectors for diffraction enhanced breast imaging
    Darambara, DG
    Speller, RD
    Sellin, P
    2001 IEEE NUCLEAR SCIENCE SYMPOSIUM, CONFERENCE RECORDS, VOLS 1-4, 2002, : 173 - 175
  • [28] Development of a dual-detector system based on a-Si:H Arrays and multi-element silicon detectors for diffraction-enhanced breast imaging
    Darambara, DG
    Speller, RD
    Sellin, P
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2002, 49 (03) : 1012 - 1016