Development of an ultrahigh-resolution Si-PM-based dual-head GAGG coincidence imaging system

被引:11
|
作者
Yamamoto, Seiichi [1 ]
Watabe, Hiroshi [2 ]
Kanai, Yasukazu [2 ]
Kato, Katsuhiko
Hatazawa, Jun [2 ,3 ]
机构
[1] Nagoya Univ, Grad Sch Med, Dept Radiol & Med Lab Sci, Higashi Ku, Nagoya, Aichi 4618673, Japan
[2] Osaka Univ, Grad Sch Med, Dept Mol Imaging Med, Osaka, Japan
[3] Osaka Univ, Grad Sch Med, Dept Nucl Med & Tracer Kinet, Osaka, Japan
关键词
Si-PM; Coincidence; Imaging; Ultra high resolution; GAGG; PET; DETECTOR;
D O I
10.1016/j.nima.2012.11.098
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A silicon photomultiplier (Si-PM) is a promising photodetector for high resolution PET systems due to its small channel size and high gain. Using Si-PMs, it will be possible to develop a high resolution imaging systems. For this purpose, we developed a small field-of-view (FOV) ultrahigh-resolution Si-PM-based dual-head coincidence imaging system for small animals and plant research. A new scintillator, Ce doped Gd3Al12Ga3O12 (GAGG), was selected because of its high light output and its emission wavelength matched with the Si-PM arrays and contained no radioactivity. Each coincidence imaging block detector consists of 0.5 x 0.5 x 5 mm(3) GAGG pixels combined with a 0.1-mm thick reflector to form a 20 x 17 matrix that was optically coupled to a Si-PM array (Hamamatsu MPPC S11064-050P) with a 1.5-mm thick light guide. The GAGG block size was 12.0 x 10.2 mm(2). Two GAGG block detectors were positioned face to face and set on a flexible arm based detector stand. All 0.5 mm GAGG pixels in the block detectors were clearly resolved in the 2-dimensional position histogram. The energy resolution was 14.4% FWHM for the Cs-137 gamma ray. The spatial resolution was 0.7 mm FWHM measured using a 0.25 mm diameter Na-22 point source. Small animal and plant images were successfully obtained. We conclude that our developed ultrahigh-resolution Si-PM-based dual-head coincidence imaging system is promising for small animal and plant imaging research. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:183 / 189
页数:7
相关论文
共 28 条
  • [1] Development of an ultrahigh-resolution Si-PM-based dual-head GAGG coincidence imaging system
    Yamamoto, Seiichi
    Watabe, Hiroshi
    Kanai, Yasukazu
    Imaizumi, Masao
    Watabe, Tadashi
    Shimosegawa, Eku
    Hatazawa, Jun
    JOURNAL OF NUCLEAR MEDICINE, 2012, 53
  • [2] Dual-head coincidence imaging resolution and influence factors
    Department of Nuclear Medicine, Cancer Hospital, FUMC and CAMS, Beijing 100021, China
    不详
    Hedianzixue Yu Tance Jishue, 2007, 2 (180-183):
  • [3] Development of ultrahigh resolution Si-PM-based PET system using 0.32 mm pixel scintillators
    Yamamoto, Seiichi
    Watabe, Hiroshi
    Watabe, Tadashi
    Ikeda, Hayato
    Kanai, Yasukazu
    Ogata, Yoshimune
    Kato, Katsuhiko
    Hatazawa, Jun
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2016, 836 : 7 - 12
  • [4] Performance comparison of Si-PM-based block detectors with different pixel sizes for an ultrahigh-resolution small-animal PET system
    Yamamoto, Seiichi
    Watabe, Hiroshi
    Hatazawa, Jun
    PHYSICS IN MEDICINE AND BIOLOGY, 2011, 56 (20): : N227 - N236
  • [5] Development of a high-resolution Si-PM-based gamma camera system
    Yamamoto, Seiichi
    Watabe, Hiroshi
    Kanai, Yasukazu
    Imaizumi, Masao
    Watabe, Tadashi
    Shimosegawa, Eku
    Hatazawa, Jun
    PHYSICS IN MEDICINE AND BIOLOGY, 2011, 56 (23): : 7555 - 7567
  • [6] Development of a Si-PM-based high-resolution PET system for small animals
    Yamamoto, Seiichi
    Imaizumi, Masao
    Watabe, Tadashi
    Watabe, Hiroshi
    Kanai, Yasukazu
    Shimosegawa, Eku
    Hatazawa, Jun
    PHYSICS IN MEDICINE AND BIOLOGY, 2010, 55 (19): : 5817 - 5831
  • [7] Development of ultrahigh resolution Si-PM-based small animal PET system using 0.32mm pixel scintillators
    Yamamoto, Seiichi
    Watabe, Hiroshi
    Watabe, Tadashi
    Ikeda, Hayato
    Kanai, Yasukazu
    Kato, Katsuhiko
    Hatazawa, Jun
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [8] Simultaneous imaging using Si-PM-based PET and MRI for development of an integrated PET/MRI system
    Yamamoto, Seiichi
    Watabe, Tadashi
    Watabe, Hiroshi
    Aoki, Masaaki
    Sugiyama, Eiji
    Imaizumi, Masao
    Kanai, Yasukazu
    Shimosegawa, Eku
    Hatazawa, Jun
    PHYSICS IN MEDICINE AND BIOLOGY, 2012, 57 (02): : N1 - N13
  • [9] Development of an ultrahigh resolution Si-PM based PET system for small animals
    Yamamoto, Seiichi
    Watabe, Hiroshi
    Kanai, Yasukazu
    Watabe, Tadashi
    Kato, Katsuhiko
    Hatazawa, Jun
    PHYSICS IN MEDICINE AND BIOLOGY, 2013, 58 (21): : 7875 - 7888
  • [10] Development of an angled Si-PM-based detector unit for positron emission mammography (PEM) system
    Nakanishi, Kouhei
    Yamamoto, Seiichi
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2016, 837 : 171 - 177