Prevalence and predictors of post-COVID-19 pulmonary fibrosis

被引:1
|
作者
Alkhayat, Khaled Fawzy [1 ,5 ]
Gadallah, Doaa [1 ]
Hasan, Mohamed Hamed [2 ]
Abdel-Gawad, Abdelhady Ragab [3 ]
Mohamed, Eman Roshdy [4 ]
Bakir, Asmaa Ramadan [1 ]
机构
[1] Sohag Univ, Sohag Univ Hosp, Dept Chest Dis & TB, Sohag, Egypt
[2] Sohag Univ, Sohag Univ Hosp, Dept Radiol, Sohag, Egypt
[3] Sohag Univ, Sohag Univ Hosp, Dept Clin Pathol, Sohag, Egypt
[4] Sohag Univ, Fac Med, Dept Publ Hlth & Community Med, Sohag, Egypt
[5] Sohag Univ, Sohag Univ Hosp, Dept Chest Dis & TB, Chest Dis, Sohag, Egypt
关键词
COVID-19; D-dimer; pulmonary fibrosis;
D O I
10.4103/ecdt.ecdt_76_21
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background Several studies are ongoing to obtain more information about post-COVID-19 (corona virus disease-19) pulmonary fibrosis. Old-aged patients are more likely to evolve lung fibrosis in COVID-19. Another risk factor is the degree of disease severity, including comorbidities, such as hypertension, diabetes, as well as lab findings, for example, lymphopenia and leukocytosis. Aims of work To assess the prevalence of post-COVID-19 pulmonary fibrosis and reveal some of its predictors. Results The study included 50 patients in the outpatient clinics of Chest and EL-Helal Hospitals with a mean age of 49.6 +/- 17.7 years. It included 32 (64%) males and 18 (36%) females. Pulmonary fibrosis was detected in 34 (68%) patients. Pulmonary fibrosis was bilateral in 24 patients and unilateral in 10 patients. Leucopenia, elevated serum ferritin, elevated D-dimer, and elevated C-reactive protein (CRP) were associated with pulmonary fibrosis (P value < 0.001). Conclusion Pulmonary fibrosis is recognized as a complication between survivors. Immune response due to lung injury by viral infection, and trials to repair are keys to the procedure of fibro genesis. Predictors of lung fibrosis involve increased lab parameters such as serum ferritin, C-reactive protein, and D-dimer.
引用
收藏
页码:481 / 484
页数:4
相关论文
共 50 条
  • [21] Case Report: Pirfenidone in the Treatment of Post-COVID-19 Pulmonary Fibrosis
    Zhou, Xianglin
    Yang, Danhui
    Kong, Xianglong
    Wei, Chengli
    LvQiu, Siqi
    Wang, Lin
    Lin, Yongkang
    Yin, Zhilan
    Zhou, Zhiguo
    Luo, Hong
    FRONTIERS IN MEDICINE, 2022, 9
  • [22] Successful Lung Transplantation for Severe Post-COVID-19 Pulmonary Fibrosis
    Hall, David J.
    Schulte, Jefree J.
    Lewis, Erik E.
    Bommareddi, Swaroop R.
    Rohrer, Charles T.
    Sultan, Samir
    Maloney, James D.
    DeCamp, Malcolm M.
    McCarthy, Daniel P.
    ANNALS OF THORACIC SURGERY, 2022, 114 (01): : E17 - E19
  • [23] Severe progression of idiopathic pulmonary fibrosis post-COVID-19 infection
    Earl, Naomi
    Schoeneberg, Dillon
    Davidson, Philip D.
    BMJ CASE REPORTS, 2021, 14 (10)
  • [24] Post-COVID-19 pulmonary fibrosis: A case series and review of literature
    Rai, Deependra K.
    Kumar, Subhash
    Sahay, Nishant
    JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE, 2021, 10 (05) : 2028 - 2031
  • [25] Post-COVID-19 pulmonary fibrosis: Mechanisms, biomarkers, and therapeutic perspectives
    Sardarni, Urvinder Kaur
    Byrareddy, Siddappa N.
    CLINICAL AND TRANSLATIONAL DISCOVERY, 2025, 5 (01):
  • [26] Pulmonary Rehabilitation for Post-COVID-19
    Aljazeeri, Jafar
    Almusally, Rayyan
    Wert, Yijin
    Abdelhalim, Mostafa
    Klinger, Cathleen
    Ramesh, Navitha
    Rahman, Taj
    JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION, 2023, 43 (06) : 438 - 443
  • [27] Pirfenidone and post-Covid-19 pulmonary fibrosis: invoked again for realistic goals
    Al-kuraishy, Hayder M.
    Batiha, Gaber El-Saber
    Faidah, Hani
    Al-Gareeb, Ali, I
    Saad, Hebatallah M.
    Simal-Gandara, Jesus
    INFLAMMOPHARMACOLOGY, 2022, 30 (06) : 2017 - 2026
  • [28] Post-COVID-19 Pulmonary Fibrosis: Facts—Challenges and Futures: A Narrative Review
    Sy Duong-Quy
    Thu Vo-Pham-Minh
    Quynh Tran-Xuan
    Tuan Huynh-Anh
    Tinh Vo-Van
    Quan Vu-Tran-Thien
    Vinh Nguyen-Nhu
    Pulmonary Therapy, 2023, 9 : 295 - 307
  • [29] Post-COVID-19 pulmonary fibrosis and its predictive factors: a prospective study
    Nabahati, Mehrdad
    Ebrahimpour, Soheil
    Khaleghnejad Tabari, Reza
    Mehraeen, Rahele
    EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE, 2021, 52 (01):
  • [30] Pirfenidone and post-Covid-19 pulmonary fibrosis: invoked again for realistic goals
    Hayder M. Al-kuraishy
    Gaber El-Saber Batiha
    Hani Faidah
    Ali I. Al-Gareeb
    Hebatallah M. Saad
    Jesus Simal-Gandara
    Inflammopharmacology, 2022, 30 : 2017 - 2026