Wound Healing Activity of Phyllanthus niruri in Albino Wistar Rats

被引：1
|
作者：
Venkateshwarlu, Goli [1 ]
Veliyath, S. K. [1 ]
Vijayabhaskar, Kanakam [2 ]
Harishbabu, K. [1 ]
Malothu, Ravi [1 ]
Sahoo, Subhas [3 ]
机构：
[1] Moonray Inst Pharmaceut Sci, Shadnagar 508001, Mahabubnagar, India
[2] Venkateshwara Inst Pharmaceut Sci, Nalgonda 508001, India
[3] Saraswathi Coll Pharmaceut Sci, Moinabad 501504, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2012年 / 24卷 / 09期
关键词：
Phyllanthus niruri; Wound healing; Excision wound; Incision wound; Povidone iodine ointment; EXTRACT;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The entire wound healing process is a complex series of events that begins at the moment of injury and can continue for months to years. The objective of present study is to investigate wound healing activity of the chloroform leaf extract of Phyllanthus niruri in albino rats using excision and incision wound models. 200 mg/kg/day of leaf extract of Phyllanthus niruri was evaluated for its wound healing activity and compared with neosporin (standard). The present investigation may be concluded that the plant Phyllanthus niruri is endowed with significantly as followed the 0, 4th, 8th, 12th, 16th, days i.e. 232.21 +/- 5.8 (0 %), 197.8 +/- 4.5 (14.85 %), 80.7 +/- 4.8 (65.5 %), 15.03 +/- 2.9 (91.9 %), 2.9 +/- 1.04 (98.8 %) wound healing activity due to the presence active constituents, there by justifying its use in the indigenous system of medicine.
引用
收藏
页码：3929 / 3930
页数：2
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