STEM CELLS Reprogramming in situ

被引:6
|
作者
De Los Angeles, Alejandro [1 ,2 ,3 ,4 ]
Daley, George Q. [1 ,2 ,3 ,4 ]
机构
[1] Childrens Hosp, Div Pediat Hematol & Oncol, Stem Cell Transplantat Program, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Howard Hughes Med Inst, Harvard Stem Cell Inst, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
关键词
DIFFERENTIATION; PLURIPOTENCY;
D O I
10.1038/nature12559
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cellular reprogramming to a stem-cell state has now been achieved in tissues of genetically engineered mice. This work signals a future for regenerative medicine in which tissue fates might be manipulated in living organisms. See Article p.340
引用
收藏
页码:309 / 310
页数:2
相关论文
共 50 条
  • [31] Epigenetic control of stem cells, reprogramming, germ cells
    Armstrong, Lyle
    JOURNAL OF ANATOMY, 2008, 212 (01) : 75 - 75
  • [32] Reprogramming Primordial Germ Cells into Pluripotent Stem Cells
    Durcova-Hills, Gabriela
    Tang, Fuchou
    Doody, Gina
    Tooze, Reuben
    Surani, M. Azim
    PLOS ONE, 2008, 3 (10):
  • [33] Reprogramming of retinoblastoma cancer cells into cancer stem cells
    Yue, Fengming
    Hirashima, Kanji
    Tomotsune, Daihachiro
    Takizawa-Shirasawa, Sakiko
    Yokoyama, Tadayuki
    Sasaki, Katsunori
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 482 (04) : 549 - 555
  • [34] Reprogramming of melanocytic cells into induced pluripotent stem cells
    Utikal, J.
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2009, 7 (09): : 841 - 842
  • [35] Reprogramming of pancreatic β cells into induced pluripotent stem cells
    Stadtfeld, Matthias
    Brennand, Kristen
    Hochedlinger, Konrad
    CURRENT BIOLOGY, 2008, 18 (12) : 890 - 894
  • [36] Nuclear reprogramming of somatic cells to pluripotent stem cells
    Tada, Takashi
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2008, 128 : 29 - 30
  • [37] Reprogramming of adult stem/progenitor cells into iPSCs without reprogramming factors
    Ebrahimi, Behnam
    JOURNAL OF MEDICAL HYPOTHESES AND IDEAS, 2015, 9 (02): : 99 - 103
  • [38] A breakthrough in stem cell research? Reprogramming somatic cells into pluripotent stem cells
    Greber, B.
    Schoeler, H.
    BUNDESGESUNDHEITSBLATT-GESUNDHEITSFORSCHUNG-GESUNDHEITSSCHUTZ, 2008, 51 (09) : 1005 - 1013
  • [39] Reprogramming of adult human neural stem cells into induced pluripotent stem cells
    XIE Li-qian
    SUN Hua-ping
    WANG Tian
    TANG Hai-liang
    WANG Pu
    ZHU Jian-hong
    YAO Zheng-wei
    FENG Xiao-yuan
    中华医学杂志(英文版), 2013, 126 (06) : 1138 - 1143
  • [40] Reprogramming of Trophoblast Stem Cells into Pluripotent Stem Cells by Oct4
    Wu, Tong
    Wang, Haitao
    He, Jing
    Kang, Lan
    Jiang, Yonghua
    Liu, Jinchao
    Zhang, Yu
    Kou, Zhaohui
    Liu, Lijun
    Zhang, Xuehong
    Gao, Shaorong
    STEM CELLS, 2011, 29 (05) : 755 - 763