The complete mitochondrial genome of the lipid-producing yeast Rhodotorula toruloides

被引：4
|
作者：
Zhou, Renhui [1 ,2 ]
Zhu, Zhiwei [3 ]
Zhang, Sufang [1 ]
Zhao, Zongbao Kent [1 ]
机构：
[1] Chinese Acad Sci, Lab Biotechnol, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
[2] Univ Chinese Acad Sci, Sch Chem Engn, 19A Yuquanlu, Beijing 100049, Peoples R China
[3] Dalian Univ Technol, Sch Bioengn, Dalian 116024, Peoples R China
来源：
FEMS YEAST RESEARCH | 2020年 / 20卷 / 06期
基金：
中国国家自然科学基金;
关键词：
mitochondrial genome; Rhodotorula toruloides; genome annotation; comparative genomics; transcriptomic analysis; RHODOSPORIDIUM-TORULOIDES; SEQUENCE; PROMOTERS;
D O I：
10.1093/femsyr/foaa048
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Mitochondria are semi-autonomous organelles with their own genome and crucial to cellular material and energy metabolism. Here, we report the complete mitochondrial genome of a lipid-producing basidiomycetous yeast Rhodotorula toruloides NP11. The mitochondrial genome of R. toruloides NP11 was assembled into a circular DNA molecule of 125937bp, encoding 15 proteins, 28 transfer RNAs, 2 ribosomal RNA subunits and 10 open reading frames with unknown function. The G + C content (41%) of the mitochondrial genome is substantially lower than that of the nuclear genome (62%) of R. toruloides NP11. Further reanalysis of the transcriptome data confirmed the transcription of four mitochondrial genes. The comparison of the mitochondrial genomes of R. toruloides NP11 and NBRC0880 revealed a significant genetic divergence. These data can complement our understanding of the genetic background of R. toruloides and provide fundamental information for further genetic engineering of this strain.
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页数：9
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