Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids

被引:17
|
作者
Yu, Meihua [1 ]
Karmakar, Surajit [1 ]
Yang, Jie [1 ]
Zhang, Hongwei [1 ]
Yang, Yannan [1 ]
Thorn, Peter [2 ]
Yu, Chengzhong [1 ]
机构
[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia
[2] Univ Queensland, Sch Biomed Sci, Brisbane, Qld 4072, Australia
基金
澳大利亚研究理事会;
关键词
DRUG-DELIVERY; INORGANIC NANOPARTICLES; IN-VIVO; MICELLES; THERAPY; CULTURE; PH;
D O I
10.1039/c3cc48416e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A facile approach has been developed to prepare ultra-small hybrid silica spheres with a diameter of similar to 10 nm, which show highly enhanced penetration ability in 3D glioma spheroids compared to conventional mesoporous silica nanoparticles.
引用
收藏
页码:1527 / 1529
页数:3
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