Gold-Catalyzed Intermolecular Oxidation of Terminal Alkynes: Simple and Efficient Synthesis of α-Mesyloxy Ketones

被引：28
|
作者：
Xie, Longyong [1 ]
Liang, Zhiwu [1 ]
Yan, Dong [1 ,2 ]
He, Weimin [1 ]
Xiang, Jiannan [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
[2] Hunan Chem Ind Vocat Technol Inst, Zhuzhou 412004, Peoples R China
来源：
SYNLETT | 2013年 / 24卷 / 14期
基金：
湖南省自然科学基金;
关键词：
alkynes; homogenous catalysis; gold; alpha-oxo gold carbine; alpha-mesyloxy ketones; ONE-POT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; PHOTOCHEMICAL-SYNTHESIS; REARRANGEMENT; HETEROCYCLES; YLIDES; ACCESS; ROUTE; CYCLOPROPANATION; CYCLOADDITION;
D O I：
10.1055/s-0033-1339337
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A variety of terminal alkynes were efficiently converted into the corresponding alpha-mesyloxy ketones through gold-catalyzed intermolecular oxidation in the presence of 3,5-dichloropyridine N-oxide as the oxidant. The reaction is proposed to proceed via alpha-oxo gold carbene intermolecular O-H insertion.
引用
收藏
页码：1809 / 1812
页数：4
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