This paper presents a design methodology for high-order class-D amplifiers, based on their similarity with sigma-delta () modulators, for which established theory and toolboxes are available. The proposed methodology, which covers the entire design flow, from specifications to component sizing, is validated with three design examples, namely a second-order, a third-order, and a fourth-order class-D amplifier. Moreover, the third-order class-D amplifier has been integrated on silicon and characterized, further confirming the validity of the whole design flow. The achieved results demonstrate that high-order class-D amplifiers can achieve total-harmonic-distortion (THD) performance compatible with the specifications of high-end audio applications (THD a parts per thousand 90 dB), which would be unfeasible with conventional first-order class-D amplifiers.