Optical coherence tomography in resolution of photoreceptor damage in multiple evanescent white dot syndrome

Multiple evanescent white dot syndrome (MEWDS) is an acute-onset chorioretinal inflammatory disease. This disorder is characterized by unilateral multiple gray-white dots of the posterior pole in young healthy women. Symptoms include blurred vision, photopsia, and visual field (VF) defects. Although the etiology of MEWDS is still unknown, most patients have spontaneous improvement in vision and fundus appearance within a period of weeks. Herein, we report a typical case of MEWDS, and describe the spontaneous resolution of photoreceptor damage during the entire course, demonstrated by serial optical coherence tomography (OCT). The OCT is a sensitive and noninvasive tool for the diagnosis and serial microstructure evaluation of patients with MEWDS. Copyright (c) 2012 Elsevier Taiwan LLC and the Chinese Medical Association. All rights reserved.