Arterial stiffness is increased in healthy subjects with a positive family history of hypertension

被引：6

作者：

Liu, Jinbo ^{[1
]}

Wang, Hongyu ^{[1
]}

Zhao, Hongwei ^{[1
]}

Liu, Huan ^{[1
]}

Li, Lihong ^{[1
]}

Zhou, Yingyan ^{[1
]}

机构：

[1] Peking Univ, Shougang Hosp, Dept Vasc Med, Beijing 100144, Peoples R China

来源：

CLINICAL AND EXPERIMENTAL HYPERTENSION | 2015年 / 37卷 / 08期

关键词：

Arterial stiffness; arteriosclerosis; family history; hypertension; pulse wave velocity; PULSE-WAVE VELOCITY; CORONARY-HEART-DISEASE; ATHEROSCLEROSIS;

D O I：

10.3109/10641963.2015.1036061

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A positive family history of hypertension is a risk factor for cardiovascular diseases. We investigated the value of pulse wave velocity (PWV) in healthy subjects with a positive family history of hypertension. 255 healthy subjects (M/F: 75/180) were divided into two groups according to without (group 1) or with (group 2) a positive family history of hypertension. Carotid-femoral pulse wave velocity (CF-PWV) was measured by Complior apparatus. Our results showed that CF-PWV was significantly higher in group 2 than in group 1 (7.90 +/- 1.31 versus 7.32 +/- 1.15m/s, p<0.001). High-density lipoprotein cholesterol (HDL-C) was significantly higher in group 1 than in group 2. Multiple linear regressions showed that age, family history, GLU, and MAP were independent influencing factors of CF-PWV in the entire study group. Our present study showed PWV is significantly higher in healthy subjects with a positive family history of hypertension. Family history might play an important role in this process.

引用

页码：622 / 626

页数：5

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