Re-differentiation of Human Articular Chondrocytes Is Not Enhanced by a Rotary Bioreactor System

被引：1
|
作者：
Barlic, A. [1 ]
Kregar-Velikonja, N. [1 ]
机构：
[1] Educell DOO, SI-1000 Ljubljana, Slovenia
来源：
FOLIA BIOLOGICA | 2008年 / 54卷 / 06期
关键词：
human articular chondrocytes; real-time PCR; rotary bioreactor system; hydrogel scaffold; tissue engineering;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating-wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems.
引用
收藏
页码：177 / 179
页数：3
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