Re-differentiation of Human Articular Chondrocytes Is Not Enhanced by a Rotary Bioreactor System

被引：1

作者：

Barlic, A. ^{[1
]}

Kregar-Velikonja, N. ^{[1
]}

机构：

[1] Educell DOO, SI-1000 Ljubljana, Slovenia

来源：

FOLIA BIOLOGICA | 2008年 / 54卷 / 06期

关键词：

human articular chondrocytes; real-time PCR; rotary bioreactor system; hydrogel scaffold; tissue engineering;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating-wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems.

引用

页码：177 / 179

页数：3

共 50 条

[1] The Critical Role of Hypoxia in the Re-Differentiation of Human Articular Chondrocytes
Martinez-Armenta, Carlos
Suarez-Ahedo, Carlos
Olivos-Meza, Anell
Camacho-Rea, Maria C.
Martinez-Gomez, Laura E.
Elizabeth Jimenez-Gutierrez, Guadalupe
Martinez-Nava, Gabriela A.
Gomez-Quiroz, Luis E.
Pineda, Carlos
Lopez-Reyes, Alberto
CELLS, 2022, 11 (16)
[2] Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes
Daniel Vonwil
Andreas Trüssel
Olivia Haupt
Samy Gobaa
Andrea Barbero
V. Prasad. Shastri
Ivan Martin
Drug Delivery and Translational Research, 2012, 2 : 351 - 362
[3] Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes
Vonwil, Daniel
Truessel, Andreas
Haupt, Olivia
Gobaa, Samy
Barbero, Andrea
Shastri, V. Prasad
Martin, Ivan
DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2012, 2 (05) : 351 - 362
[4] TGFβ inhibition during expansion phase increases the chondrogenic re-differentiation capacity of human articular chondrocytes
Narcisi, R.
Signorile, L.
Verhaar, J. A. N.
Giannoni, P.
van Osch, G. J. V. M.
OSTEOARTHRITIS AND CARTILAGE, 2012, 20 (10) : 1152 - 1160
[5] Evidence for re-differentiation of human chondrocytes seeded on a hyaluronan derivative scaffold
B Grigolo
G Lisignoli
A Piacentini
M Fiorini
L Roseti
EO Major
M Duca
A Pavesio
A Facchini
Arthritis Research & Therapy, 3 (Suppl 1)
[6] Evidence for re-differentiation of human chondrocytes seeded on a hyaluronan derivative scaffold
Grigolo, B.
Lisignoli, G.
Piacentini, A.
Fiorini, M.
Roseti, L.
Major, E. O.
Duca, M.
Pavesio, A.
Facchini, A.
ARTHRITIS RESEARCH & THERAPY, 2001, 3
[7] Alterations in CD44 isoforms and HAS expression in human articular chondrocytes during the de- and re-differentiation processes
Albrecht, Christian
Schlegel, Werner
Eckl, Peter
Jagersberger, Tamara
Sadeghi, Kambis
Berger, Angelika
Vecsei, Vilmos
Marlovits, Stefan
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2009, 23 (02) : 253 - 259
[8] EFFECT OF HUMAN SYNOVIAL FLUID IN MODELS OF IN VITRO CHONDROGENIC RE-DIFFERENTIATION OF HUMAN PRIMARY CHONDROCYTES
Galeano-Garces, C.
Riester, S. M.
Camilleri, E. T.
Ryan, H. S.
Smith, J.
Sampen, I. H.
Karperien, M.
van Wijnen, A. J.
OSTEOARTHRITIS AND CARTILAGE, 2016, 24 : S166 - S166
[9] Donor ethnicity, sex, and age impact chondrogenic re-differentiation capacity: a multi-demographic study of human articular chondrocytes in vitro
Veenendaal, Laura
Liu, Valery Yizhuo
Lacey, Cameron
Lim, Khoon S.
Hooper, Gary J.
Woodfield, Tim B. F.
Lindberg, Gabriella C. J.
JOURNAL OF THE ROYAL SOCIETY OF NEW ZEALAND, 2024,
[10] Culture of Human Septal Chondrocytes in a Rotary Bioreactor
Reuther, Marsha S.
Wong, Van W.
Briggs, Kristen K.
Chang, Angela A.
Nguyen, Quynhhoa T.
Schumacher, Barbara L.
Masuda, Koichi
Sah, Robert L.
Watson, Deborah
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2012, 147 (04) : 661 - 667

← 1 2 3 4 5 →