Synthesis of 3a, 4-dihydro-8-substituted-3H-isoxazolo [c-4,3] thiapyrano [5,6-3,2] quinolines

被引：15
|
作者：
Prabhuswamy, B [1 ]
Ambekar, SY [1 ]
机构：
[1] Univ Mysore, Dept Postgrad Studies Chem, Mysore 570006, Karnataka, India
来源：
SYNTHETIC COMMUNICATIONS | 1999年 / 29卷 / 20期
关键词：
D O I：
10.1080/00397919908085980
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Condensation of 2-chloro-3-formylquinoline 1a-c with allylthiol 2 afforded 2-allysulfanyl-3-formylquinolines 3a-c, Oximation followed by oxidation of 3a-c with NaOCl or chloramine-T, in cold or mercuric acetate resulted in the formation of respective nitrile oxides, which underwent insitu intramolecular 1,3-dipolar cycloaddition reaction and afforded the title compounds 5a-c in high yield.
引用
收藏
页码：3477 / 3485
页数：9
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