The Reaction of N-Isocyaniminotriphenylphosphorane with 2-Oxopropylbenzoate (or 4-Bromobenzoate) and a Primary Amine in the Presence of (E)-Cinnamic Acid Derivatives: A One-Pot Efficient Four-Component Reaction for the Synthesis of 2-(Arylamino)-2-(5-aryl-1-ethenyl-1,3,4-oxadiazol-2-yl) Propyl Benzoate (or 4-Bromobenzoate) Derivatives

被引：5
|
作者：
Ramazani, Ali [1 ]
Ahmadi, Yavar [1 ]
Nasrabadi, Fatemeh Zeinali [1 ]
Rouhani, Morteza [2 ]
机构：
[1] Zanjan Univ, Dept Chem, Zanjan, Iran
[2] Islamic Azad Univ, Zanjan Branch, Young Researchers Club, Zanjan, Iran
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2013年 / 50卷 / 06期
关键词：
SUBSTITUTED 1,3,4-OXADIAZOLE DERIVATIVES; STABILIZED PHOSPHORUS YLIDES; AROMATIC CARBOXYLIC-ACIDS; X-RAY-STRUCTURE; STEREOSELECTIVE-SYNTHESIS; MULTICOMPONENT REACTIONS; 3-COMPONENT REACTION; (N-ISOCYANIMINO)TRIPHENYLPHOSPHORANE;
D O I：
10.1002/jhet.1563
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reactions of N-isocyaniminotriphenylphosphorane with 2-oxopropylbenzoate (or 2-oxopropyl 4-bromobenzoate) in the presence of (E)-cinnamic acids and primary amines proceed smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions were observed.
引用
收藏
页码：1294 / 1298
页数：5
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