The nature of neonatal status epilepticus - a clinician's perspective

被引：5
|
作者：
Dlugos, Dennis J. [1 ]
机构：
[1] Univ Penn, Perelman Sch Med, Childrens Hosp Philadelphia, Div Neurol, Philadelphia, PA 19104 USA
来源：
EPILEPSY & BEHAVIOR | 2015年 / 49卷
关键词：
Neonatal seizures; Status epilepticus; SEIZURES; CLASSIFICATION;
D O I：
10.1016/j.yebeh.2015.04.025
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
Neonatal status epilepticus occurs within the substrate of the hyperexcitable newborn brain and is usually provoked by acute CNS derangements, although status can also be the presentation of early-life epilepsy. Provoked neonatal status usually resolves within a few days, with or without treatment, but new data suggests that status is associated with adverse outcomes, even after controlling for underlying disease severity and MRI structural brain injury. Novel treatments may be needed to improve seizure control and outcome, given the characteristics of neurotransmission in the newborn brain. (C) 2015 Elsevier Inc. All rights reserved
引用
收藏
页码：88 / 89
页数：2
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