Laser-induced fluorescence imaging of subsurface tissue structures with a volume holographic spatial-spectral imaging system

被引:34
|
作者
Luo, Yuan [1 ,2 ]
Gelsinger-Austin, Paul J. [2 ]
Watson, Jonathan M. [3 ]
Barbastathis, George [3 ]
Barton, Jennifer K. [1 ,2 ,4 ]
Kostuk, Raymond K. [1 ,2 ]
机构
[1] Univ Arizona, Dept Elect & Comp Engn, Tucson, AZ 85721 USA
[2] Univ Arizona, Coll Opt Sci, Tucson, AZ 85721 USA
[3] MIT, Dept Mech Engn, Cambridge, MA 02139 USA
[4] Univ Arizona, Dept Biomed Engn, Tucson, AZ 85721 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1364/OL.33.002098
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A three-dimensional imaging system incorporating Multiplexed holographic gratings to visualize fluorescence tissue structures is presented. Holographic gratings formed in volume recording materials such as a phenanthrenquinone poly(methyl methacrylate) photopolymer have narrowband angular and spectral transmittance filtering properties that enable obtaining spatial-spectral information within an object. We demonstrate this imaging system's ability to obtain multiple depth-resolved fluorescence images simultaneously. (c) 2008 Optical Society of America
引用
收藏
页码:2098 / 2100
页数:3
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