A Proline-Tryptophan turn in the intrinsically disordered domain 2 of NS5A protein is essential for Hepatitis C virus RNA replication

被引：0
|
作者：
Dujardin, Marie [1 ]
Madan, Vanesa [2 ]
Montserret, Roland [3 ]
Ahuja, Puneet [1 ]
Huvent, Isabelle [1 ]
Launay, Helene [1 ]
Bartenschlager, Ralf [2 ]
Penin, Francois [3 ]
Lippens, Guy [1 ]
Hanoulle, Xavier [1 ]
机构：
[1] Univ Lille, CNRS, UMR 8576, UGSF, Lille, France
[2] Heidelberg Univ, Mol Virol, Dept Infect Dis, D-69115 Heidelberg, Germany
[3] Univ Lyon 1, CNRS, UMR 5086, IBCP,LabEx Ecofect, F-69622 Villeurbanne, France
来源：
PROTEIN SCIENCE | 2015年 / 24卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
PF-006
引用
收藏
页码：121 / 122
页数：2
相关论文
共 50 条
  • [21] Correlation between NS5A Dimerization and Hepatitis C Virus Replication
    Lim, Precious J.
    Chatterji, Udayan
    Cordek, Daniel
    Sharma, Suresh D.
    Garcia-Rivera, Jose A.
    Cameron, Craig E.
    Lin, Kai
    Targett-Adams, Paul
    Gallay, Philippe A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (36) : 30861 - 30873
  • [22] A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication
    Sklan, Ella H.
    Staschke, Kirk
    Oakes, Tina M.
    Elazar, Menashe
    Winters, Mark
    Aroeti, Benjamin
    Danieli, Tsafi
    Glenn, Jeffrey S.
    JOURNAL OF VIROLOGY, 2007, 81 (20) : 11096 - 11105
  • [23] The NS5A protein of bovine viral diarrhea virus contains an essential zinc-binding site similar to that of the hepatitis C virus NS5A protein
    Tellinghuisen, Timothy L.
    Paulson, Matthew S.
    Rice, Charles M.
    JOURNAL OF VIROLOGY, 2006, 80 (15) : 7450 - 7458
  • [24] Domain 2 of Hepatitis C Virus Protein NS5A Activates Glucokinase and Induces Lipogenesis in Hepatocytes
    Perrin-Cocon, Laure
    Kundlacz, Cindy
    Jacquemin, Clemence
    Hanoulle, Xavier
    Aublin-Gex, Anne
    Figl, Marianne
    Manteca, Jeremy
    Andre, Patrice
    Vidalain, Pierre-Olivier
    Lotteau, Vincent
    Diaz, Olivier
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (02)
  • [25] Antigenic heterogeneity of the hepatitis C virus NS5A protein
    Dou, XG
    Talekar, G
    Chang, J
    Dai, X
    Li, LX
    Bonafonte, MT
    Holloway, B
    Fields, HA
    Khudyakov, YE
    JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (01) : 61 - 67
  • [26] The NS5A protein of hepatitis C virus is a zinc metalloprotein
    Tellinghuisen, TL
    Marcotrigiano, J
    Gorbalenya, AE
    Rice, CM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (47) : 48576 - 48587
  • [27] Serine Phosphorylation of the Hepatitis C Virus NS5A Protein Controls the Establishment of Replication Complexes
    Ross-Thriepland, Douglas
    Mankouri, Jamel
    Harris, Mark
    JOURNAL OF VIROLOGY, 2015, 89 (06) : 3123 - 3135
  • [28] Hepatitis C virus NS5A: tales of a promiscuous protein
    Macdonald, A
    Harris, M
    JOURNAL OF GENERAL VIROLOGY, 2004, 85 : 2485 - 2502
  • [29] Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication
    Elazar, M
    Cheong, KH
    Liu, P
    Greenberg, HB
    Rice, CM
    Glenn, JS
    JOURNAL OF VIROLOGY, 2003, 77 (10) : 6055 - 6061
  • [30] HEPATITIS C VIRUS: Effect Of NS5A On The NS5B in vitro Replication Reaction
    Quezada, Elizabeth M.
    Kane, Caroline M.
    FASEB JOURNAL, 2008, 22
12345