Bone Marrow Mesenchymal Stem Cells (BMSCs) and Motor Function Recovery from Spinal Cord Injury

被引:0
|
作者
Liu Ruilian [1 ]
Xie Jun [1 ]
机构
[1] Yichun Univ, Coll Phys Educ, Yichun 336000, Jiangxi, Peoples R China
来源
PROCEEDINGS OF THE 2012 INTERNATIONAL SYMPOSIUM - SPORTS INNOVATION AND DEVELOPMENT OF UNIVERSITIES AND COLLEGES | 2012年
关键词
Bone marrow mesenchymal stem cells (BM-MSCs); Spinal cord injury; Motor function; Recovery; STROMAL CELLS; TRANSPLANTATION;
D O I
暂无
中图分类号
G40 [教育学];
学科分类号
040101 ; 120403 ;
摘要
Function recovery from spinal cord injury has always been a difficult issue puzzling scientific workers on spinal cord. Stem Cell Transplantation (SCT) is considered one of the latest and most promising therapies. In particular, BM-MSCs lay the foundation for the recovery of damaged spinal cord function with their advantages of self-replication abilities, multi-differentiation potential, transplantable property, low immunity quality and etc. This paper mainly focuses on the clinical application and scientific research achievements of BMSCs transplantation technology on patients suffering from spinal cord injury and aims to extract findings related to the usage of BMSCs in function recovery process after spinal cord injury and to provide theoretical basis for patients with spinal cord injury in late-stage motor function recovery. The study indicates that the combination of BMSCs transplantation technology and united transplantation technology effectively accelerates the motor function recovery of patients with spinal cord injury, especially when employing BMSCs along with such substances as other medicines and neurotrophic factors, function recovery from spinal cord injury appears to be more efficiently promoted. In this way, more favorable effects are shown compared with simply using BMSCs transplantation method.
引用
收藏
页码:235 / 240
页数:6
相关论文
共 50 条
  • [21] Comparison among bone marrow mesenchymal stem and mononuclear cells to promote functional recovery after spinal cord injury in rabbits
    Braga Fonseca, Antonio Filipe
    Scheffer, Jussara Peters
    Giraldi-Guimaraes, Arthur
    Coelho, Barbara Paula
    Medina, Raphael Mansur
    Abreu Oliveira, Andre Lacerda
    ACTA CIRURGICA BRASILEIRA, 2017, 32 (12) : 1026 - 1035
  • [22] Bone marrow mesenchymal stem cell transplantation for treatment of spinal cord injury
    Liu, Yu
    Zhang, Boai
    Song, Yi
    Deng, Yubin
    Jia, Yanjie
    Gong, Qiyong
    NEURAL REGENERATION RESEARCH, 2011, 6 (13) : 978 - 982
  • [23] Vascular Endothelial Growth Factor-Transfected Bone Marrow Mesenchymal Stem Cells Improve the Recovery of Motor and Sensory Functions of Rats With Spinal Cord Injury
    Liu, Xiao
    Xu, Wenqi
    Zhang, Zhengzheng
    Liu, He
    Lv, Lanxin
    Han, Dong
    Liu, Lin
    Yao, Aimin
    Xu, Tie
    SPINE, 2020, 45 (07) : E364 - E372
  • [24] Editor’s Note: Adult bone marrow mesenchymal and neural crest stem cells are chemoattractive and accelerate motor recovery in a mouse model of spinal cord injury
    Virginie Neirinckx
    Gulistan Agirman
    Cécile Coste
    Alice Marquet
    Valérie Dion
    Bernard Rogister
    Rachelle Franzen
    Sabine Wislet
    Stem Cell Research & Therapy, 12 (1)
  • [26] Changes of Related Signal Pathway Genes of Bone Marrow-Derived Mesenchymal Stem Cells(BMSCs)-Derived OBs After Spinal Cord Injury
    Zhang, Jiye
    Qiu, Weifu
    Gao, Xiaoqiang
    Cai, Hanhua
    Zheng, Feng
    Chen, Xuanhuang
    JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 2020, 10 (11) : 1628 - 1633
  • [27] Treatment of Spinal Cord Injury with Bone Marrow-Derived, Cultured Autologous Mesenchymal Stem Cells
    Jeon, Sang Ryong
    Park, Jin Hoon
    Lee, Jung Hwan
    Kim, Dae Yul
    Kim, Hyun Soo
    Sung, Inn Young
    Choi, Gyong Hyo
    Jeon, Min Ho
    Kim, Guang Gook
    TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2010, 7 (03) : 316 - 322
  • [28] Repeated intravenous infusion of mesenchymal stem cells enhances recovery of motor function in a rat model with chronic spinal cord injury
    Kurihara, Kota
    Sasaki, Masanori
    Nagahama, Hiroshi
    Obara, Hisashi
    Fukushi, Ryunosuke
    Hirota, Ryosuke
    Yoshimoto, Mitsunori
    Teramoto, Atsushi
    Kocsis, Jeffery D.
    Yamashita, Toshihiko
    Honmou, Osamu
    BRAIN RESEARCH, 2023, 1817
  • [29] Bone marrow mesenchymal stem cells combined with minocycline improve spinal cord injury in a rat model
    Chen, Dayong
    Zeng, Wei
    Fu, Yunfeng
    Gao, Meng
    Lv, Guohua
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 8 (10): : 11957 - 11969
  • [30] Spinal cord injury repair using mesenchymal stem cells derived from bone marrow in mice: A stereological study
    Khodabandeh, Zahra
    Mehrabani, Davood
    Dehghani, Farzaneh
    Gashmardi, Nooshin
    Erfanizadeh, Mahboobeh
    Zare, Shahrokh
    Bozorg-Ghalati, Farzaneh
    ACTA HISTOCHEMICA, 2021, 123 (05)