Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data

被引：215
|
作者：
Robertson, Charles E. [1 ,2 ]
Harris, J. Kirk [2 ,3 ]
Wagner, Brandie D. [2 ,4 ]
Granger, David [5 ]
Browne, Kathy [5 ]
Tatem, Beth [5 ]
Feazel, Leah M. [6 ]
Park, Kristin [1 ]
Pace, Norman R. [1 ]
Frank, Daniel N. [2 ,6 ]
机构：
[1] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA
[2] Univ Colorado Microbiome Res Consortium, Aurora, CO 80045 USA
[3] Univ Colorado Anschutz Med Campus, Dept Pediat, Aurora, CO 80045 USA
[4] Colorado Sch Publ Hlth, Dept Biostat & Informat, Aurora, CO 80045 USA
[5] Incubix Inc, Boulder, CO 80301 USA
[6] Univ Colorado Anschutz Med Campus, Dept Med, Aurora, CO 80045 USA
来源：
BIOINFORMATICS | 2013年 / 29卷 / 23期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1093/bioinformatics/btt526
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Studies of the human microbiome, and microbial community ecology in general, have blossomed of late and are now a burgeoning source of exciting research findings. Along with the advent of next-generation sequencing platforms, which have dramatically increased the scope of microbiome-related projects, several high-performance sequence analysis pipelines (e. g. QIIME, MOTHUR, VAMPS) are now available to investigators for microbiome analysis. The subject of our manuscript, the graphical user interface-based Explicet software package, fills a previously unmet need for a robust, yet intuitive means of integrating the outputs of the software pipelines with user-specified metadata and then visualizing the combined data.
引用
收藏
页码：3100 / 3101
页数：2
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