Human Papillomavirus Vaccine Safety in Pediatric Patients: An Evaluation of the Vaccine Adverse Event Reporting System

被引：12

作者：

Borja-Hart, Nancy L. ^{[1
]}

Benavides, Sandra ^{[1
]}

Christensen, Crystal ^{[1
]}

机构：

[1] Nova SE Univ, Coll Pharm, Ft Lauderdale, FL 33328 USA

来源：

ANNALS OF PHARMACOTHERAPY | 2009年 / 43卷 / 02期

关键词：

Gardasil; human papillomavirus; pediatrics; VAERS; PARTICLE VACCINE; QUADRIVALENT VACCINE; UNITED-STATES; TYPE-16; IMMUNOGENICITY; ADOLESCENTS; TRIAL; WOMEN;

D O I：

10.1345/aph.1L492

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Recent news reports have linked the human papillomavirus (HPV) vaccine to serious adverse events (AEs) in children and adolescents. We used the Vaccine Adverse Event Reporting System (VAERS) database to extract postmarketing AEs reported in patients who received the vaccine. Since approval of the HPV vaccine in the US, 3174 AEs occurring in children and adolescents (aged 6-17 y) have been reported to the VAERS. Of these, 191 (6%) were deemed to be serious. Although these AEs are of significant concern, more research is required before they can be directly correlated with the vaccine.

引用

页码：356 / 359

页数：4

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