A gut-heart connection in cardiometabolic regulation

被引：22
|
作者：
Buglioni, Alessia [1 ]
Burnett, John C., Jr. [1 ]
机构：
[1] Mayo Clin & Mayo Fdn, Div Cardiovasc Dis, Cardiorenal Res Lab, Rochester, MN 55905 USA
来源：
NATURE MEDICINE | 2013年 / 19卷 / 05期
关键词：
ATRIAL-NATRIURETIC-PEPTIDE; HUMAN ADIPOCYTES; BLOOD-PRESSURE;
D O I：
10.1038/nm.3196
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new study establishes a link between glucagon-like peptide-1 (GLP-1) release from the gut and the cardiac hormone atrial natriuretic peptide, which lowers blood pressure. As GLP-1 receptor agonists are used to control glycemia in patients with type 2 diabetes, this new gut-heart axis suggests a role of these agents in overall cardiovascular homeostasis (pages 567–575).
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页码：534 / 536
页数：3
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