Bone repair and stem cells

被引：29

作者：

Ono, Noriaki ^{[1
]}

Kronenberg, Henry M. ^{[2
,3
]}

机构：

[1] Univ Michigan, Dept Orthodont & Pediat Dent, Sch Dent, Ann Arbor, MI 48109 USA

[2] Massachusetts Gen Hosp, Endocrine Unit, Boston, MA 02114 USA

[3] Harvard Med Sch, Boston, MA 02114 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2016年 / 40卷

基金：

美国国家卫生研究院;

关键词：

OSTEOBLAST DIFFERENTIATION; MARROW; PRECURSORS; PERIOSTEUM; CARTILAGE; OSTERIX; CBFA1; SOX9; MICE;

D O I：

10.1016/j.gde.2016.06.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Bones are an important component of vertebrates; they grow explosively in early life and maintain their strength throughout life. Bones also possess amazing capabilities to repair - the bone is like new without a scar after complete repair. In recent years, a substantial progress has been made in our understanding on mammalian bone stem cells. Mouse genetic models are powerful tools to understand the cell lineage, giving us better insights into stem cells that regulate bone growth, maintenance and repair. Recent findings about these stem cells raise new questions that require further investigations.

引用

页码：103 / 107

页数：5

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