Chikungunya Virus Inhibitor Study based on Molecular Docking Experiments

被引:0
|
作者
Saraiva, A. A. [2 ,6 ]
Jeferson, Soares [1 ]
Miranda, Castro [1 ]
Moura Sousa, Jose Vigno [1 ]
Fonseca Ferreira, N. M. [3 ,4 ]
Batista Neto, J. E. S. [6 ]
Soares, Salviano [3 ]
Valente, Antonio [2 ,5 ]
机构
[1] UESPI Univ State Piaui, Piripiri, Brazil
[2] Univ Tras Os Montes & Alto Douro, Vila Real, Portugal
[3] Coimbra Polytech ISEC, Coimbra, Portugal
[4] Polytech Inst Porto, Inst Engn, Knowledge Engn & Decis Support Res Ctr GECAD, Porto, Portugal
[5] INESC TEC Technol & Sci, Porto, Portugal
[6] Univ Sao Paulo, Sao Carlos, Brazil
关键词
Chikungunya; Molecular; Docking; REPLICATION;
D O I
10.5220/0009118602000205
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Chikungunya virus disease transmitted by the sting of the mosquito 'Aedes aegypti' presenting an epidemic in some regions. In order to have an early diagnosis and the best treatment technique, it establishes the study of inhibitors for laboratory elaboration of a drug from molecular docking. As a result you have a better chance of using Suramin followed by Silibin.
引用
收藏
页码:200 / 205
页数:6
相关论文
共 50 条
  • [21] Isatin based thiosemicarbazide derivatives as potential inhibitor of α-glucosidase, synthesis and their molecular docking study
    Rahim, Fazal
    Taha, Muhammad
    Iqbal, Naveed
    Hayat, Shawkat
    Qureshi, Faiza
    Uddin, Imad
    Zaman, Khalid
    Rab, Abdur
    Wadood, Abdul
    Uddin, Nizam
    Nawaz, Muhammad
    Shah, Syed Adnan Ali
    Khan, Khalid Mohammed
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1222
  • [22] Enhanced Molecular Surveillance of Chikungunya Virus
    Fischer, Carlo
    de Lamballerie, Xavier
    Drexler, Jan Felix
    MSPHERE, 2019, 4 (04):
  • [23] Cell Culture and Molecular Docking Analysis to Determine the Antiviral Activity of Folklore Medicinal Plants Against Chikungunya Virus
    Kumar, Sukender
    Kaushik, Samander
    Garg, Munish
    CURRENT DRUG DELIVERY, 2024,
  • [24] The Antifungal Itraconazole Is a Potent Inhibitor of Chikungunya Virus Replication
    Policastro, Lucca R.
    Dolci, Isabela
    Godoy, Andre S.
    Silva Junior, Jose V. J.
    Ruiz, Uriel E. A.
    Santos, Igor A.
    Jardim, Ana C. G.
    Samby, Kirandeep
    Burrows, Jeremy N.
    Wells, Timothy N. C.
    Gil, Laura H. V. G.
    Oliva, Glaucius
    Fernandes, Rafaela S.
    VIRUSES-BASEL, 2022, 14 (07):
  • [25] Molecular architecture of the Chikungunya virus replication complex
    Tan, Yaw Bia
    Chmielewski, David
    Law, Michelle Cheok Yien
    Zhang, Kuo
    He, Yu
    Chen, Muyuan
    Jin, Jing
    Luo, Dahai
    SCIENCE ADVANCES, 2022, 8 (48)
  • [26] Molecular and serological diagnosis of Chikungunya virus infection
    Grivard, P.
    Le Roux, K.
    Laurent, P.
    Fianu, A.
    Perrau, J.
    Gigan, J.
    Hoarau, G.
    Grondin, N.
    Staikowsky, F.
    Favier, F.
    Michault, A.
    PATHOLOGIE BIOLOGIE, 2007, 55 (10): : 490 - 494
  • [27] Molecular modeling, simulation and docking study of ebola virus glycoprotein
    Ahmad, Nasir
    Farman, Aqsa
    Badshah, Syed Lal
    Rahman, Ata Ur
    Rashid, Haroon Ur
    Khan, Khalid
    JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2017, 72 : 266 - 271
  • [28] An In Silico Study Based on QSAR and Molecular Docking and Molecular Dynamics Simulation for the Discovery of Novel Potent Inhibitor against AChE
    Khedraoui, Meriem
    Abchir, Oussama
    Nour, Hassan
    Yamari, Imane
    Errougui, Abdelkbir
    Samadi, Abdelouahid
    Chtita, Samir
    PHARMACEUTICALS, 2024, 17 (07)
  • [29] Spectral characterisation, antiviral activities, in silico ADMET and molecular docking of the compounds isolated from Tectona grandis to chikungunya virus
    Sangeetha, K.
    Purushothaman, Indu
    Rajarajan, S.
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 87 : 302 - 310
  • [30] Identification and molecular docking of novel chikungunya virus NSP4 inhibitory peptides from camel milk proteins
    Alguridi, Hassan I.
    Alzahrani, Faisal
    Almalki, Safar
    Zamzami, Mazin A.
    Altayb, Hisham N.
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 42 (19): : 9961 - 9976