Phase I study of T cells redirected to EGFRvIII with a chimeric antigen receptor in patients with EGFRvIII plus glioblastoma

被引：0
|
作者：
O'Rourke, Donald M.
Nasrallah, MacLean P.
Morrissette, Jennifer
Melenhorst, Jan J.
Lacey, Simon F.
Mansfield, Keith
Martinez-Lage, Maria
Desai, Arati
Brem, Steven
Maloney, Eileen
Mohan, Suyash
Wang, Sumei
Verma, Gaurav
Navenot, Jean-Marc
Shen, Angela
Zheng, Zhaohui
Levine, Bruce L.
Okada, Hideho
June, Carl H.
Maus, Marcela V.
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-LB-083
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-083
引用
收藏
页数：3
相关论文
共 50 条
  • [31] Chimeric antigen receptor containing ICOS signaling domain mediates specific and efficient antitumor effect of T cells against EGFRvIII expressing glioma
    Shen, Chan-Juan
    Yang, Yu-Xiu
    Han, Ethan Q.
    Cao, Na
    Wang, Yun-Fei
    Wang, Yi
    Zhao, Ying-Ying
    Zhao, Li-Ming
    Cui, Jian
    Gupta, Puja
    Wong, Albert J.
    Han, Shuang-Yin
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2013, 6
  • [32] D2C7-CAR: A NOVEL, DUAL-SPECIFIC CHIMERIC ANTIGEN RECEPTOR T CELL WITH HIGH SPECIFICITY FOR EGFR AND EGFRVIII IMPROVES SURVIVAL IN EGFR/EGFRVIII GLIOBLASTOMA AND EGFR OVER-EXPRESSING MEDULLOBLASTOMA
    Wilson, Zach
    Wilkinson, Daniel
    Ryan, Katherine
    Chandramohan, Vidya
    Bigner, Darrell
    Fecci, Peter
    NEURO-ONCOLOGY, 2023, 25
  • [33] Efficacy of osimertinib plus bevacizumab in glioblastoma patients with simultaneous EGFR amplification and EGFRvIII mutation
    Cardona, Andres F.
    Jaramillo-Velasquez, Daniel
    Ruiz-Patino, Alejandro
    Polo, Carolina
    Jimenez, Enrique
    Hakim, Fernando
    Gomez, Diego
    Fernando Ramon, Juan
    Cifuentes, Hernando
    Armando Mejia, Juan
    Salguero, Fernando
    Ordonez, Camila
    Munoz, Alvaro
    Bermudez, Sonia
    Useche, Nicolas
    Pineda, Diego
    Ricaurte, Luisa
    Lucia Zatarain-Barron, Zyanya
    Rodriguez, July
    Avila, Jenny
    Rojas, Leonardo
    Jaller, Elvira
    Sotelo, Carolina
    Garcia-Robledo, Juan Esteban
    Santoyo, Nicolas
    Rolfo, Christian
    Rosell, Rafael
    Arrieta, Oscar
    JOURNAL OF NEURO-ONCOLOGY, 2021, 154 (03) : 353 - 364
  • [34] EGFRvIII expression defines a distinct subtype of glioblastoma: A study of 268 patients
    Pelloski, CE
    Yung, WA
    Colman, H
    Zhang, L
    Lin, E
    Woo, SY
    Yang, H
    Ledoux, A
    Aldape, KD
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 63 (02): : S68 - S68
  • [35] Efficacy of osimertinib plus bevacizumab in glioblastoma patients with simultaneous EGFR amplification and EGFRvIII mutation
    Andrés F. Cardona
    Daniel Jaramillo-Velásquez
    Alejandro Ruiz-Patiño
    Carolina Polo
    Enrique Jiménez
    Fernando Hakim
    Diego Gómez
    Juan Fernando Ramón
    Hernando Cifuentes
    Juan Armando Mejía
    Fernando Salguero
    Camila Ordoñez
    Álvaro Muñoz
    Sonia Bermúdez
    Nicolas Useche
    Diego Pineda
    Luisa Ricaurte
    Zyanya Lucia Zatarain-Barrón
    July Rodríguez
    Jenny Avila
    Leonardo Rojas
    Elvira Jaller
    Carolina Sotelo
    Juan Esteban Garcia-Robledo
    Nicolas Santoyo
    Christian Rolfo
    Rafael Rosell
    Oscar Arrieta
    Journal of Neuro-Oncology, 2021, 154 : 353 - 364
  • [36] Chimeric antigen receptor (CAR)-redirected T cells: is there a place for them in infectious diseases?
    Mancini, N.
    Sautto, G. A.
    Clementi, N.
    Burioni, R.
    Clementi, M.
    CLINICAL MICROBIOLOGY AND INFECTION, 2015, 21 (08) : 715 - 716
  • [37] The update of chimeric antigen receptor-T cells therapy in glioblastoma
    Chou, Chi-Jen
    Lin, Chun-Fu
    Chen, Yi-Wei
    Huang, Pin-, I
    Yang, Yi-Ping
    Wang, Mong-Lien
    Hung, Kai-Feng
    Lee, Yi-Yen
    JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, 2020, 83 (05) : 442 - 445
  • [38] Enhanced the antitumor effects of chimeric antigen receptor T cells in glioblastoma
    Ogunnaike, E. A.
    Valdivia, A.
    Yazdimamaghani, M.
    Leon, E.
    Du, H.
    Khagi, S.
    Gu, Z.
    Savoldo, B.
    Ligler, F. S.
    Hingtgen, S.
    Dotti, G.
    MOLECULAR BIOLOGY OF THE CELL, 2023, 34 (02) : 569 - 569
  • [39] Use of Chimeric Antigen Receptor T Cells as a Potential Therapeutic for Glioblastoma
    Khan, Muhammad Babar
    Chakraborty, Shamik
    Boockvar, John Andrew
    NEUROSURGERY, 2017, 80 (05) : N33 - N34
  • [40] PHASE I STUDY OF CHIMERIC ANTIGEN RECEPTOR-ENGINEERED T CELLS TARGETING IL13Rα2 FOR THE TREATMENT OF GLIOBLASTOMA
    Brown, Christine
    Alizadeh, Darya
    Starr, Renate
    Weng, Lihong
    Wagner, Jamie
    Naranjo, Araceli
    Blanchard, Suzette
    Kilpatrick, Julie
    Simpson, Jennifer
    Ressler, Julie Ann
    Jensen, Michael
    Portnow, Jana
    D'Apuzzo, Massimo
    Barish, Michael
    Forman, Stephen
    Badie, Behnam
    NEURO-ONCOLOGY, 2016, 18 : 20 - 20
12345