Phase I study of T cells redirected to EGFRvIII with a chimeric antigen receptor in patients with EGFRvIII plus glioblastoma

被引：0
|
作者：
O'Rourke, Donald M.
Nasrallah, MacLean P.
Morrissette, Jennifer
Melenhorst, Jan J.
Lacey, Simon F.
Mansfield, Keith
Martinez-Lage, Maria
Desai, Arati
Brem, Steven
Maloney, Eileen
Mohan, Suyash
Wang, Sumei
Verma, Gaurav
Navenot, Jean-Marc
Shen, Angela
Zheng, Zhaohui
Levine, Bruce L.
Okada, Hideho
June, Carl H.
Maus, Marcela V.
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-LB-083
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-083
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Pilot study of T cells redirected to EGFRvIII with a chimeric antigen receptor in patients with EGFRvIII plus glioblastoma.
    O'Rourke, Donald M.
    Nasrallah, MacLean
    Morrissette, Jennifer J.
    Melenhorst, Jan J.
    Lacey, Simon F.
    Mansfield, Keith
    Martinez-Lage, Maria
    Desal, Arati Suvas
    Brem, Steven
    Maloney, Eileen
    Mohan, Suyash
    Wang, Sumei
    Verma, Gaurav
    Navenot, Jean-Marc
    Shen, Angela
    Zheng, Zhaohui
    Levine, Bruce
    Okada, Hideho
    June, Carl H.
    Maus, Marcela Valderrama
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [2] T Cells Redirected to EGFRvIII with a Chimeric Antigen Receptor Engraft, Traffic and Mediate Antigen Loss in Patients with EGFRvIII plus Glioblastoma
    Nasrallah, MacLean
    Martinez-Lage, Maria
    O'Rourke, Donald
    Desai, Arati
    Morrissette, Jennifer
    Brem, Steven
    Maloney, Eileen
    Shen, Angela
    Mansfield, Keith
    Mohan, Suyash
    Wang, Sumei
    Verma, Gaurav
    Lacey, Simon
    Melenhorst, Jan
    Navenot, Jean-Marc
    Zheng, Zhaohui
    Levine, Bruce
    Okada, Hideho
    June, Carl
    Maus, Marcela
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2016, 75 (06): : 584 - 584
  • [3] Allogeneic EGFRvIII chimeric antigen receptor T cells for treatment of glioblastoma
    Wong, Oi Kwan
    Dusseaux, Mathilde
    Ma, Jing-Tyan
    Au, Melinda
    Leduc, Sophie
    Chou, Joyce
    Yu, Jessica M.
    Bateman, Marjorie
    Pertel, Thomas
    Lindquist, Kevin C.
    Smith, Julianne
    Sasu, Barbra
    Liu, Shu-Hui
    CANCER RESEARCH, 2017, 77
  • [4] EGFRVIII and EGFR targeted chimeric antigen receptor T cell therapy in glioblastoma
    Sterner, Robert C.
    Sterner, Rosalie M.
    FRONTIERS IN ONCOLOGY, 2024, 14
  • [5] Selective Targeting of Glioblastoma with EGFRvIII/EGFR Bitargeted Chimeric Antigen Receptor T Cell
    Jiang, Hua
    Gao, Huiping
    Kong, Juan
    Song, Bo
    Wang, Peng
    Shi, Bizhi
    Wang, Huamao
    Li, Zonghai
    CANCER IMMUNOLOGY RESEARCH, 2018, 6 (11) : 1314 - 1326
  • [6] Generation of regulable EGFRvIII targeted chimeric antigen receptor T cells for adoptive cell therapy of glioblastoma
    Zheng, Yan
    Gao, Ning
    Fu, Yu-Long
    Zhang, Bing-Yong
    Li, Xiu-Ling
    Gupta, Puja
    Wong, Albert J.
    Li, Tian-Fang
    Han, Shuang-Yin
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 507 (1-4) : 59 - 66
  • [7] Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma
    Goff, Stephanie L.
    Morgan, Richard A.
    Yang, James C.
    Sherry, Richard M.
    Robbins, Paul F.
    Restifo, Nicholas P.
    Feldman, Steven A.
    Lu, Yong-Chen
    Lu, Lily
    Zheng, Zhili
    Xi, Liqiang
    Epstein, Monica
    McIntyre, Lori S.
    Malekzadeh, Parisa
    Raffeld, Mark
    Fine, Howard A.
    Rosenberg, Steven A.
    JOURNAL OF IMMUNOTHERAPY, 2019, 42 (04) : 126 - 135
  • [8] Anti-EGFRvIII Chimeric Antigen Receptor-Modified T Cells for Adoptive Cell Therapy of Glioblastoma
    Ren, Pei-pei
    Li, Ming
    Li, Tian-fang
    Han, Shuang-yin
    CURRENT PHARMACEUTICAL DESIGN, 2017, 23 (14) : 2113 - 2116
  • [9] Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma
    Abbott, Rebecca C.
    Iliopoulos, Melinda
    Watson, Katherine A.
    Arcucci, Valeria
    Go, Margareta
    Hughes-Parry, Hannah E.
    Smith, Pete
    Call, Melissa J.
    Cross, Ryan S.
    Jenkins, Misty R.
    CLINICAL & TRANSLATIONAL IMMUNOLOGY, 2023, 12 (03)
  • [10] DEVELOPMENT OF EGFRVIII AND EGFR DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME
    Ruff, Michael
    Sakemura, Reona
    Manriquez-Roman, Claudia
    Hefazi-Torghabeh, Mehrdad
    Schick, Kendall
    Michelle, Cox
    Can, Ismail
    Horvei, Paulina
    Siegler, Elizabeth
    Tapper, Erin
    Kenderian, Saad
    NEURO-ONCOLOGY, 2020, 22 : 65 - 65
12345