Immune Factors in Breast Milk and the Development of Atopic Disease

被引：54
|
作者：
Iyengar, Shuba R. [1 ]
Walker, W. A. [2 ]
机构：
[1] Harvard Univ, Sch Med, Dept Pediat,Dept Nutr, Massachusetts Gen Hosp Children,Pediat Allergy Im, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Pediat,Dept Nutr, Massachusetts Gen Hosp Children,Mucosal Immunol L, Boston, MA 02115 USA
来源：
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2012年 / 55卷 / 06期
基金：
美国国家卫生研究院;
关键词：
allergy; breast milk; breast-feeding; hypoallergenic formulas; probiotics; 1ST; 3; YEARS; FATTY-ACIDS; RISK-FACTOR; DERMATITIS; PREVENTION; ALLERGY; CHILDREN; METAANALYSIS; PROBIOTICS; CHILDHOOD;
D O I：
10.1097/MPG.0b013e3182617a9d
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Breast-feeding provides protection against infections and contains numerous factors that modulate and promote the development of the infant immune system. These factors include secretory IgA, antimicrobial proteins like CD14, cytokines, and fatty acids. Studies examining the role of breast-feeding in the development of allergic disease in infants demonstrate potentially protective as well as neutral or nonprotective effects, likely due to the heterogeneity in their study design. In this overview, we explore the potential role of immune factors in the breast milk, as well as selected probiotics, in the development of allergy.
引用
收藏
页码：641 / 647
页数：7
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