Stereoselective Synthesis of Tetrahydroquinolines Through an Imino-Ene Cyclization Reaction

被引：12
|
作者：
Bondalapati, Somasekhar [1 ]
Indukuri, Kiran [1 ]
Ghosh, Priya [1 ]
Saikia, Anil K. [1 ]
机构：
[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 2013卷 / 05期
关键词：
Synthetic methods; Nitrogen heterocycles; Cyclization; Diastereoselectivity; Lewis acids; ENANTIOSELECTIVE TOTAL-SYNTHESIS; AZA-PRINS-CYCLIZATION; SOLUTION-PHASE; CARBONYL-ENE; SOLID-PHASE; DERIVATIVES; ALKALOIDS; CATALYSIS; HETEROCYCLES; BENZASTATINS;
D O I：
10.1002/ejoc.201201363
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Tetrahydroquinolines have been efficiently synthesized in good yields with excellent stereoselectivity. The reaction between alpha-allylic anilines and aldehydes proceeds through an imino-ene cyclization that is mediated by boron trifluoride-diethyl ether.
引用
收藏
页码：952 / 956
页数：5
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