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Diagnostic and Pathophysiological Impact of Myocardial MIBG Scintigraphy in Parkinson's Disease
被引:16
|作者:
Spiegel, Joerg
[1
]
机构:
[1] Univ Saarland, Dept Neurol, D-66421 Homburg, Germany
关键词:
CARDIAC SYMPATHETIC DENERVATION;
I-123-MIBG SCINTIGRAPHY;
LEWY BODIES;
DIFFERENTIAL-DIAGNOSIS;
CLINICAL-DIAGNOSIS;
METAIODOBENZYLGUANIDINE;
DEGENERATION;
DYSFUNCTION;
PHEOCHROMOCYTOMA;
ACCURACY;
D O I:
10.4061/2010/295346
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Myocardial MIBG scintigraphy is established in the diagnosis and differential diagnosis of Parkinson's disease (PD). Numerous studies address the pathophysiological impact of myocardial MIBG scintigraphy: the myocardial MIBG uptake correlates with the clinical phenotype of PD; the background of this phenomenon is unclear. Furthermore MIBG scintigraphy enables to study the extracranial Lewy body type-degeneration. In combination with cerebral dopamine transporter imaging, MIBG scintigraphy allows to correlate cerebral and extracranial Lewy body type-degeneration in PD.
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页数:6
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