Diagnostic and Pathophysiological Impact of Myocardial MIBG Scintigraphy in Parkinson's Disease

被引:16
|
作者
Spiegel, Joerg [1 ]
机构
[1] Univ Saarland, Dept Neurol, D-66421 Homburg, Germany
关键词
CARDIAC SYMPATHETIC DENERVATION; I-123-MIBG SCINTIGRAPHY; LEWY BODIES; DIFFERENTIAL-DIAGNOSIS; CLINICAL-DIAGNOSIS; METAIODOBENZYLGUANIDINE; DEGENERATION; DYSFUNCTION; PHEOCHROMOCYTOMA; ACCURACY;
D O I
10.4061/2010/295346
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Myocardial MIBG scintigraphy is established in the diagnosis and differential diagnosis of Parkinson's disease (PD). Numerous studies address the pathophysiological impact of myocardial MIBG scintigraphy: the myocardial MIBG uptake correlates with the clinical phenotype of PD; the background of this phenomenon is unclear. Furthermore MIBG scintigraphy enables to study the extracranial Lewy body type-degeneration. In combination with cerebral dopamine transporter imaging, MIBG scintigraphy allows to correlate cerebral and extracranial Lewy body type-degeneration in PD.
引用
收藏
页数:6
相关论文
共 50 条
  • [1] Reliability of MIBG myocardial scintigraphy in the diagnosis of Parkinson's disease
    Nagayama, H
    Hamamoto, M
    Ueda, M
    Nagashima, J
    Katayama, Y
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76 (02): : 249 - 251
  • [2] Combination of transcranial sonography, olfactory testing, and MIBG myocardial scintigraphy as a diagnostic indicator for Parkinson's disease
    Izawa, M. O.
    Miwa, H.
    Kajimoto, Y.
    Kondo, T.
    EUROPEAN JOURNAL OF NEUROLOGY, 2012, 19 (03) : 411 - 416
  • [3] MIBG myocardial scintigraphy in pre-motor Parkinson's disease: A review
    Sakakibara, Ryuji
    Tateno, Fuyuki
    Kishi, Masahiko
    Tsuyusaki, Yohei
    Terada, Hitoshi
    Inaoka, Tsutomu
    PARKINSONISM & RELATED DISORDERS, 2014, 20 (03) : 267 - 273
  • [4] Diagnostic cutoff points for 123I-MIBG myocardial scintigraphy in a Caucasian population with Parkinson’s disease
    África Muxí
    Pilar Paredes
    Ignacio Navales
    Francesc Valldeoriola
    Carles Gaig
    Francisco Lomeña
    Andres de la Cerda
    Oriol Solà
    Beatriz Domenech
    Eduardo Tolosa
    Francesca Pons
    European Journal of Nuclear Medicine and Molecular Imaging, 2011, 38 : 1139 - 1146
  • [5] Diagnostic cutoff points for 123I-MIBG myocardial scintigraphy in a Caucasian population with Parkinson's disease
    Muxi, Africa
    Paredes, Pilar
    Navales, Ignacio
    Valldeoriola, Francesc
    Gaig, Carles
    Lomena, Francisco
    de la Cerda, Andres
    Sola, Oriol
    Domenech, Beatriz
    Tolosa, Eduardo
    Pons, Francesca
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2011, 38 (06) : 1139 - 1146
  • [6] Diagnostic value of MIBG cardiac scintigraphy for the diagnosis of Parkinson disease
    Abbasi, M.
    Tafakhori, A.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 : S567 - S567
  • [7] Myocardial MIBG scintigraphy in genetic Parkinson's disease as a model for Lewy body disorders
    Gabilondo, Inigo
    Llorens, Veronica
    Rodriguez, Trinidad
    Fernandez, Manuel
    Perez Concha, Tomas
    Acera, Marian
    Tijero, Beatriz
    Murueta-Goyena, Ane
    del Pino, Rocio
    Cortes, Jesus
    Carlos Gomez-Esteban, Juan
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2019, 46 (02) : 376 - 384
  • [8] Myocardial MIBG scintigraphy in genetic Parkinson’s disease as a model for Lewy body disorders
    Iñigo Gabilondo
    Verónica Llorens
    Trinidad Rodriguez
    Manuel Fernández
    Tomas Pérez Concha
    Marian Acera
    Beatriz Tijero
    Ane Murueta-Goyena
    Rocío del Pino
    Jesús Cortés
    Juan Carlos Gómez-Esteban
    European Journal of Nuclear Medicine and Molecular Imaging, 2019, 46 : 376 - 384
  • [9] Myocardial MIBG scintigraphy may predict the course of motor symptoms in Parkinson's disease
    Dorschner, Julia
    Farmakis, Georgios
    Behnke, Stefanie
    Hellwig, Dirk
    Schneider, Susanne
    Fassbender, Klaus
    Kirsch, Carl-Martin
    Dillmann, Ulrich
    Spiegel, Joerg
    PARKINSONISM & RELATED DISORDERS, 2011, 17 (05) : 372 - 375
  • [10] Transcranial sonography of substantia nigra and MIBG myocardial scintigraphy in patients with early Parkinson's disease
    Kajimoto, Y.
    Hironishi, M.
    Miwa, H.
    Kondo, T.
    MOVEMENT DISORDERS, 2006, 21 : S592 - S592