AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications

被引:34
|
作者
Gao, Hui [1 ]
Zhao, Xin [2 ]
Chen, Sijie [1 ]
机构
[1] Karolinska Inst, Ming Wai Lau Ctr Reparat Med, Hong Kong, Hong Kong, Peoples R China
[2] Hong Kong Polytech Univ, Dept Biomed Engn, Hong Kong, Hong Kong, Peoples R China
来源
MOLECULES | 2018年 / 23卷 / 02期
关键词
fluorescent nanomaterials; AIE; bioimaging; cell tracing; theranosis; AGGREGATION-INDUCED EMISSION; ULTRABRIGHT ORGANIC DOTS; SILICA NANOPARTICLES; IN-VITRO; CHITOSAN NANOPARTICLES; DRUG-DELIVERY; CANCER-CELLS; BIOCOMPATIBLE NANOPARTICLES; BIOMEDICAL APPLICATIONS; BIOIMAGING APPLICATIONS;
D O I
10.3390/molecules23020419
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In recent years, luminogens with the feature of aggregation-induced emission (AIEgen) have emerged as advanced luminescent materials for fluorescent nanomaterial preparation. AIEgen-based nanomaterials show enhanced fluorescence efficiency and superior photostability, which thusly offer unique advantages in biological applications. In this review, we will summarize the fabrication methods of AIEgen-based nanomaterials and their applications in in vitro/in vivo imaging, cell tracing, photodynamic therapy and drug delivery, focusing on the recent progress.
引用
收藏
页数:20
相关论文
共 50 条
  • [21] Microfluidic fabrication of fluorescent nanomaterials: A review
    Lin, Liangliang
    Yin, Yijian
    Starostin, Sergey A.
    Xu, Hujun
    Li, Chengdong
    Wu, Kejun
    He, Chaohong
    Hessel, Volker
    CHEMICAL ENGINEERING JOURNAL, 2021, 425
  • [22] Identification of Potent Caspase-8 Inhibitors from a Library of Fluorescent Natural Products Screened by an AIEgen-Based Light-Up Probe
    Lin, Hao
    Yang, Wan-Qi
    Ye, Zi
    Zhang, Chong-Jing
    CHEMBIOCHEM, 2019, 20 (10) : 1292 - 1296
  • [23] AIEgen-Based Lifetime-Probes for Precise Furin Quantification and Identification of Cell Subtypes
    Jia, Hui
    Ding, Defang
    Hu, Jingjing
    Dai, Jun
    Yang, Juliang
    Li, Guogang
    Lou, Xiaoding
    Xia, Fan
    ADVANCED MATERIALS, 2021, 33 (45)
  • [24] Fluorescent nanomaterials for biomedical applications
    Ganguly, Sayan
    Das, Poushali
    Parameswaranpillai, Jyotishkumar
    Maity, Priti Prasanna
    FRONTIERS IN MATERIALS, 2023, 10
  • [25] From Two, to Three, to Multi-Color Switches: Developing AIEgen-Based Mechanochromic Materials
    Meng, Xiao
    Chen, Changqing
    Qi, Guangyu
    Li, Xue
    Wang, Kai
    Zou, Bo
    Ma, Yuguo
    CHEMNANOMAT, 2017, 3 (08): : 569 - 574
  • [26] Rapid and high-throughput testing of antifungal susceptibility using an AIEgen-based analytical system
    Ge, Xiaoxue
    Gao, Meng
    He, Bairong
    Cao, Nannan
    Li, Kerun
    Liu, Yong
    Tang, Sanmei
    Liu, Kai
    Zhang, Jing
    Hu, Fang
    Zheng, Lei
    Situ, Bo
    BIOMATERIALS, 2022, 287
  • [27] AIEgen-based metal-organic frameworks as sensing "toolkit" for identification and analysis of energetic compounds
    Zhu, Long-yi
    Zhu, Bin
    Wan, Ying
    Deng, Sheng-yuan
    Yu, Zhang-dong
    Zhang, Chong
    Luo, Jun
    ENERGETIC MATERIALS FRONTIERS, 2022, 3 (04): : 257 - 265
  • [28] Recent advances in AIEgen-based luminescent metal-organic frameworks and covalent organic frameworks
    Ma, Li
    Feng, Xiao
    Wang, Shan
    Wang, Bo
    MATERIALS CHEMISTRY FRONTIERS, 2017, 1 (12) : 2474 - 2486
  • [29] AIEgen-lipid structures: Assembly and biological applications
    Cao, Hongqian
    Yang, Yang
    Li, Junbai
    AGGREGATE, 2020, 1 (01): : 69 - 79