Seroepidemiological surveillance of Burkholderia pseudomallei in Bangladesh

被引:8
|
作者
Maude, Rapeephan R. [1 ]
Maude, Richard J. [1 ,2 ]
Ghose, Aniruddha [3 ]
Amin, Md Robed [4 ]
Islam, Md Belalul [5 ]
Ali, Mohammad [6 ]
Bari, Md Shafiqul [7 ]
Majumder, Md Ishaque [8 ]
Wuthiekanan, Vanaporn [1 ]
Dondorp, Arjen M. [1 ,2 ]
Bailey, Robin L. [9 ]
Day, Nicholas P. J. [1 ,2 ]
Abul Faiz, M. [8 ]
机构
[1] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit MORU, Bangkok 10400, Thailand
[2] Churchill Hosp, Nuffield Dept Clin Med, CCVTM, Ctr Trop Med, Oxford OX3 7LJ, England
[3] Chittagong Med Coll, Chittagong, Bangladesh
[4] Dhaka Med Coll, Dhaka, Bangladesh
[5] Comilla Med Coll, Comilla, Bangladesh
[6] Shaheed Ziaur Rahman Med Coll, Bogra, Bangladesh
[7] MAG Osmani Med Coll, Sylhet, Bangladesh
[8] Sir Salimullah Med Coll, Dhaka, Bangladesh
[9] London Sch Hyg & Trop Med, London WC1, England
基金
英国惠康基金;
关键词
Burkholderia pseudomallei; Melioidosis; Indirect haemagglutination assay; Seroprevalence; Epidemiological surveillance; Bangladesh; MELIOIDOSIS;
D O I
10.1016/j.trstmh.2012.06.003
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Melioidosis (Burkholderia pseudomallei infection) has yet to be demonstrated systematically in Bangladesh. A prospective, cross-sectional serological survey was conducted in 2010 at six Bangladeshi hospitals. Age, gender, occupation and residential address were recorded. Of 1244 patients, 359(28.9%) were positive for B. pseudomallei by indirect haemagglutination assay. Farmers had an increased risk of seropositivity (risk ratio = 1.4, 95% CI 1.0-1.8; p = 0.03). There was no clear geographic clustering of seropositives. Melioidosis should be considered as a possible cause of febrile illness in Bangladesh. Further studies are needed to establish the incidence of clinical disease and distribution of environmental risk. (c) 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:576 / 578
页数:3
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