Unmodified chiral primary amino alcohol as a new ligand for enantioselective alkynylation of aldehydes

被引：12
|
作者：
Xu, Zhou [1 ]
Mao, Jincheng [1 ]
Zhang, Yawen [1 ]
机构：
[1] Suzhou Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
来源：
CATALYSIS COMMUNICATIONS | 2008年 / 10卷 / 01期
关键词：
Amino alcohol; Asymmetric alkynylation; Phenylacetylene; Enantioselectivity; Propargylic alcohols;
D O I：
10.1016/j.catcom.2008.08.006
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The unmodified available chiral amino alcohol 14 in combination with Ti((OPr)-Pr-i)(4) was found to catalyze the reaction of an alkynylzinc reagent with various aldehydes to generate chiral propargylic alcohols with moderate to good yields and enantioselectivities. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码：113 / 117
页数：5
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