Mnk targeting enhances vulnerability of medulloblastoma stem -like cancer cells to PI3K-pllOalpha inhibition

被引：0
|
作者：
Bell, Jonathan B.
Eckerdt, Frank
Ma, Quanhong
Clymer, Jessica R.
Goldman, Stewart
Hashizume, Rintaro
Platanias, Leonidas C.
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-LB-009
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-009
引用
收藏
页数：3
相关论文
共 50 条
  • [21] TARGETING GLIOBLASTOMA STEM CELLS VIA INHIBITION OF PI3K/AKT PATHWAY ALONE AND IN COMBINATION WITH AUTOPHAGY BLOCKADE
    Graham, Regina
    Benito, Daniel
    Soni, Neil
    Uddin, Raisa
    Zhang, Baoyu
    Walters, Winston
    Bregy, Amade
    Komotar, Ricardo
    NEURO-ONCOLOGY, 2014, 16
  • [22] Targeting MLL Methyltransferases Enhances the Antitumor Effects of PI3K Inhibition in Hormone Receptor-positive Breast Cancer
    Jones, Robert B.
    Farhi, Jonathan
    Adams, Miranda
    Parwani, Kiran K.
    Cooper, Garrett W.
    Zecevic, Milica
    Lee, Richard S.
    Hong, Andrew L.
    Spangle, Jennifer M.
    CANCER RESEARCH COMMUNICATIONS, 2022, 2 (12): : 1569 - 1578
  • [23] PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
    Hambardzumyan, Dolores
    Becher, Oren J.
    Rosenblum, Marc K.
    Pandolfi, Pier Paolo
    Manova-Todorova, Katia
    Holland, Eric C.
    GENES & DEVELOPMENT, 2008, 22 (04) : 436 - 448
  • [24] BET Inhibition-Induced GSK3β Feedback Enhances Lymphoma Vulnerability to PI3K Inhibitors
    Derenzini, Enrico
    Mondello, Patrizia
    Erazo, Tatiana
    Portelinha, Ana
    Liu, Yuxuan
    Scallion, Mary
    Asgari, Zahra
    Philip, John
    Hilden, Patrick
    Valli, Debora
    Rossi, Alessandra
    Djaballah, Hakim
    Ouerfelli, Ouathek
    de Stanchina, Elisa
    Seshan, Venkatraman E.
    Hendrickson, Ronald C.
    Younes, Anas
    CELL REPORTS, 2018, 24 (08): : 2155 - 2166
  • [25] Co-targeting toll-like receptor and PI3K survival signaling pathways in stem-like castration resistant prostate cancer cells
    Oseni, Saheed Oluwasina
    Branly, Rolando
    Pavlovic, Mirjana
    Kumi-Diaka, James
    CANCER RESEARCH, 2018, 78 (13)
  • [26] PI3K Inhibition Enhances Doxorubicin-Induced Apoptosis in Sarcoma Cells
    Marklein, Diana
    Graab, Ulrike
    Naumann, Ivonne
    Yan, Tiandong
    Ridzewski, Rosalie
    Nitzki, Frauke
    Rosenberger, Albert
    Dittmann, Kai
    Wienands, Juergen
    Wojnowski, Leszek
    Fulda, Simone
    Hahn, Heidi
    PLOS ONE, 2012, 7 (12):
  • [27] Expression of Concern to: Identifying and targeting cancer stem cells in leiomyosarcoma: prognostic impact and role to overcome secondary resistance to PI3K/mTOR inhibition
    Benjamin Fourneaux
    Aurélien Bourdon
    Bérengère Dadone
    Carlo Lucchesi
    Scott R. Daigle
    Elodie Richard
    Audrey Laroche-Clary
    François Le Loarer
    Antoine Italiano
    Journal of Hematology & Oncology, 12
  • [28] Inhibition of doxorubicin-induced HER3-PI3K-AKT signalling enhances apoptosis of ovarian cancer cells
    Bezler, Martin
    Hengstler, Jan G.
    Ullrich, Axel
    MOLECULAR ONCOLOGY, 2012, 6 (05) : 516 - 529
  • [29] Simultaneous Inhibition of EGFR and PI3K Enhances Radiosensitivity in Human Breast Cancer
    Li, Ping
    Zhang, Qing
    Torossian, Artour
    Li, Zhao-bin
    Xu, Wen-cai
    Lu, Bo
    Fu, Shen
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 83 (03): : E391 - E397
  • [30] Targeting Epigenetic Resistance Mechanisms to PI3 Kinase Inhibition in Leukemic Stem Cells
    Glushakow-Smith, Shira
    Kaur, Imit
    Sidoli, Simone
    Hemmati, Shayda
    Angeles, Ellen
    Sinclair, Taneisha
    Battle, Aaliyah
    Verma, Amit
    Gritsman, Kira
    BLOOD, 2023, 142
12345