Concomitant tetrasomy 3q and trisomy 18 in CD5-, CD13+ chronic lymphocytic leukemia

被引：6

作者：

Specchia, G ^{[1
]}

Albano, F

Anelli, L

Storlazzi, CT

Monaco, M

Capalbo, S

Rocchi, M

Liso, V

机构：

[1] Univ Bari, Policlin, Dept Hematol, I-70124 Bari, Italy

[2] Univ Foggia, Dept Hematol, I-71100 Foggia, Italy

[3] Hosp Foggia, I-71100 Foggia, Italy

[4] Univ Bari, DAPEG, Sez Genet, Policlin, I-70124 Bari, Italy

来源：

CANCER GENETICS AND CYTOGENETICS | 2002年 / 133卷 / 02期

关键词：

D O I：

10.1016/S0165-4608(01)00583-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chronic lymphocytic leukemia (CLL) associated with myeloid antigens on the surface of B neoplastic cells is a recently identified immunologic variant confined to patients with CD5 negative B-CLL. We describe the case of a 61-year-old female diagnosed with CD5(-), CD13(+) B-CLL with a tetrasomy 3q revealed by fluorescence in situ hybridization analysis, in addition to trisomy 18. To our knowledge, this is the first reported case of B-CLL with this kind of cytogenetic abnormality. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

页码：160 / 163

页数：4

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