Concomitant tetrasomy 3q and trisomy 18 in CD5-, CD13+ chronic lymphocytic leukemia

被引：6
|
作者：
Specchia, G [1 ]
Albano, F
Anelli, L
Storlazzi, CT
Monaco, M
Capalbo, S
Rocchi, M
Liso, V
机构：
[1] Univ Bari, Policlin, Dept Hematol, I-70124 Bari, Italy
[2] Univ Foggia, Dept Hematol, I-71100 Foggia, Italy
[3] Hosp Foggia, I-71100 Foggia, Italy
[4] Univ Bari, DAPEG, Sez Genet, Policlin, I-70124 Bari, Italy
来源：
CANCER GENETICS AND CYTOGENETICS | 2002年 / 133卷 / 02期
关键词：
D O I：
10.1016/S0165-4608(01)00583-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chronic lymphocytic leukemia (CLL) associated with myeloid antigens on the surface of B neoplastic cells is a recently identified immunologic variant confined to patients with CD5 negative B-CLL. We describe the case of a 61-year-old female diagnosed with CD5(-), CD13(+) B-CLL with a tetrasomy 3q revealed by fluorescence in situ hybridization analysis, in addition to trisomy 18. To our knowledge, this is the first reported case of B-CLL with this kind of cytogenetic abnormality. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码：160 / 163
页数：4
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