A change in the physical state of a nonequilibrium blood plasma protein film in patients with carcinoma

被引:46
|
作者
Rapis, E [1 ]
机构
[1] Tel Aviv Univ, IL-64239 Ramat Aviv, Israel
关键词
Carcinoma; Phase Transition; Physical State; Liquid Crystal; Plasma Protein;
D O I
10.1134/1.1470608
中图分类号
O59 [应用物理学];
学科分类号
摘要
Pronounced changes in the physical phase and in the phase transition dynamics of proteins in drying blood plasma are observed. The morphologies (topologies) of these nonequilibrium films in donors and in patients with various types of metastatic carcinoma qualitatively differ by the process of protein film self-assembly and by symmetry type. New types of defects and solid crystals appear, liquid crystals persist for a long time, etc. The microscopic examination of the drying protein plasma topology can be used for diagnosing metastatic carcinoma. (C) 2002 MAIK "Nauka / Interperiodica".
引用
收藏
页码:510 / 512
页数:3
相关论文
共 50 条
  • [31] NEW DIAGNOSTIC AND PROGNOSTIC PLASMA BIOMARKERS FOR PATIENTS WITH HEPATOCELLULAR CARCINOMA IDENTIFIED BY PROTEIN PROFILING
    Serra, I.
    Estanyol, J. M.
    Sarrias, M. -R.
    Ragull, S.
    Huertas, C.
    Miquel, M.
    Coll, S.
    Pons, F.
    Rubin, A.
    Bartoli, R.
    Barriocanal, A.
    Odena, G.
    Aldeguer, X.
    Morillas, R.
    Bachs, O.
    Planas, R.
    Sala, M.
    Armengol, C.
    JOURNAL OF HEPATOLOGY, 2013, 58 : S443 - S443
  • [32] Plasma Protein Biomarkers of Hepatocellular Carcinoma in HCV-Infected Alcoholic Patients with Cirrhosis
    Ferrin, Gustavo
    Rodriguez-Peralvarez, Manuel
    Aguilar-Melero, Patricia
    Ranchal, Isidora
    Llamoza, Camilo
    Linares, Clara I.
    Gonzalez-Rubio, Sandra
    Muntane, Jordi
    Briceno, Javier
    Lopez-Cillero, Pedro
    Luis Montero-Alvarez, Jose
    de la Mata, Manuel
    PLOS ONE, 2015, 10 (03):
  • [33] The change of plasma interleukines and liver functions in hepatocellular carcinoma Patients after transcatheter arterial chemoembolization
    Tsai, C. C.
    Cheng, K. S.
    Chou, F. T.
    Lai, H. C.
    Shih, H. C.
    Tang, H. L.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2009, 24 : A183 - A183
  • [34] Film thickness dependence of protein adsorption from blood serum and plasma onto poly(sulfobetaine)-grafted surfaces
    Yang, Wei
    Chen, Shengfu
    Cheng, Gang
    Vaisocherova, Hana
    Xue, Hong
    Li, Wei
    Zhang, Jinli
    Jiang, Shaoyi
    LANGMUIR, 2008, 24 (17) : 9211 - 9214
  • [35] Blood plasma main proteins stability of patients with ductal carcinoma in post-surgery period
    Nemsadze, Gia
    Lezhava, Teimuraz
    Gorgoshidze, Maya
    Kiladze, Maya
    Gogelia, Nestan
    Khachidze, Davit
    Lomidze, Eteri
    Monaselidze, Jamlet
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016, 9 (02): : 1338 - 1345
  • [36] Blood plasma protein regeneration as influenced by infection, digestive disturbances, thyroid, and food proteins - Deficiency state related to protein depletion
    Madden, SC
    Winslow, PM
    Howland, JW
    Whipple, GH
    JOURNAL OF EXPERIMENTAL MEDICINE, 1937, 65 (03): : 431 - 454
  • [37] Quality of life after hepatectomy in patients with hepatocellular carcinoma: Implication of change in hepatic protein synthesis
    Ueno, S
    Tanabe, G
    Nuruki, K
    Yoshidome, S
    Kubo, F
    Kihara, K
    Aoki, D
    Aikou, T
    HEPATO-GASTROENTEROLOGY, 2002, 49 (44) : 492 - 496
  • [38] CHANGE IN THE PHYSICAL STATE OF PLATELET PLASMA-MEMBRANES UPON IONOPHORE A23187 ACTIVATION - A FLUORESCENCE POLARIZATION STUDY
    BOUDET, G
    LEVYTOLEDANO, S
    MACLOUF, J
    RENDU, F
    SALESSE, R
    BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 812 (01) : 243 - 248
  • [39] Stability of direct oral anticoagulants in whole blood and plasma from patients in steady state treatment
    McGrail, Rie
    Revsholm, Jesper
    Nissen, Peter H.
    Grove, Erik L.
    Hvas, Anne-Mette
    THROMBOSIS RESEARCH, 2016, 148 : 107 - 110
  • [40] THE STATE OF PLATELET AND PLASMA HEMOSTASIS AS A PREDICTOR OF CORONARY BLOOD FLOW IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
    Dukhin, O. A.
    Kalinskaya, A., I
    Rusakovich, G. L.
    Anisimova, A. S.
    Netylko, J. E.
    Polyakov, P. A.
    Vasiljeva, E. Yu
    Shpektor, A., V
    KARDIOLOGIYA, 2022, 62 (07) : 31 - 37