Staphylococcus aureus Biofilms Promote Horizontal Transfer of Antibiotic Resistance

被引:240
|
作者
Savage, Victoria J.
Chopra, Ian
O'Neill, Alex J. [1 ]
机构
[1] Univ Leeds, Antimicrobial Res Ctr, Leeds, W Yorkshire, England
关键词
D-AMINO ACIDS; PLASMID TRANSFER; REACTOR;
D O I
10.1128/AAC.02008-12
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Growth as a biofilm facilitates the emergence of antibiotic resistance by mutation in Staphylococcus aureus. Here we demonstrate that biofilm growth of this species also dramatically increases horizontal transfer of plasmid-borne antibiotic resistance determinants by conjugation/mobilization and that standard laboratory practices to induce conjugation in staphylococci achieve optimal efficiency owing to the presence of a biofilm.
引用
收藏
页码:1968 / 1970
页数:3
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