Enhanced proliferation and tyrosine kinase pathway engagement in 4-1BB domain-containing CAR T cells

被引：0

作者：

Karlsson, H. ^{[1
]}

Svensson, E. ^{[1
]}

Lindqvist, C. ^{[1
]}

Hambardzumyan, K. ^{[1
]}

Larsson, R. ^{[2
]}

Jarvius, M. ^{[2
]}

Stromberg, U. Ohlsson ^{[2
,3
]}

Savoldo, B. ^{[4
]}

Dotti, G. ^{[4
]}

Loskog, A. ^{[1
]}

机构：

[1] Uppsala Univ, Sci Life Lab, Dept Immunol Genet & Pathol, Uppsala, Sweden

[2] Uppsala Univ, Dept Med Sci, Uppsala, Sweden

[3] Univ Uppsala Hosp, Sect Hematol, Uppsala, Sweden

[4] Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA

来源：

HUMAN GENE THERAPY | 2013年 / 24卷 / 12期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：A163 / A163

页数：1

共 50 条

[21] Activation of anti-tumor NK cells by gamma delta T lymphocytes through 4-1BB engagement
Chapoval, Andrei
Maniar, Amudhan
Zhang, Xiaoyu
Gastman, Brian R.
Pauza, C. David
Strome, Scott E.
JOURNAL OF IMMUNOLOGY, 2009, 182
[22] Enhanced CD4+ T cell responses in 4-1BB deficient mice
Lee, SW
Vella, AT
Kwon, BS
Croft, M
FASEB JOURNAL, 2005, 19 (04): : A908 - A908
[23] 4-1BB enhances proliferation of beryllium-specific T cells in the lung of subjects with chronic beryllium disease
Mack, Douglas G.
Lanham, Allison K.
Palmer, Brent E.
Maier, Lisa A.
Watts, Tania H.
Fontenot, Andrew P.
JOURNAL OF IMMUNOLOGY, 2008, 181 (06): : 4381 - 4388
[24] Transcriptional Signatures of CD28-ζ and 4-1BB-ζ Containing CAR T Cells
Boroughs, Angela
Marjanovic, Nemanja D.
Castano, Ana P.
Lorrey, Selena J.
Jerby, Livnat
Morris, Robert
Regev, Aviv
Maus, Marcela V.
MOLECULAR THERAPY, 2018, 26 (05) : 336 - 336
[25] 4-1BB costimulation ameliorates exhaustion and prolongs in vivo persistence of chimeric antigen receptor (CAR) expressing T cells
Long, Adrienne H.
Haso, Waleed M.
Smith, Jillian P.
Walker, Alec J.
Fry, Terry J.
Orentas, Rimas J.
Mackall, Crystal L.
CANCER RESEARCH, 2015, 75
[26] Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies
Mamonkin, Maksim
Mukherjee, Malini
Srinivasan, Madhuwanti
Sharma, Sandhya
Gomes-Silva, Diogo
Mo, Feiyan
Krenciute, Giedre
Orange, Jordan S.
Brenner, Malcolm K.
CANCER IMMUNOLOGY RESEARCH, 2018, 6 (01) : 47 - 58
[27] A DIRECT SIGNALING PATHWAY THROUGH TYROSINE KINASE ACTIVATION OF SH2 DOMAIN-CONTAINING TRANSCRIPTION FACTORS
FU, XY
JOURNAL OF LEUKOCYTE BIOLOGY, 1995, 57 (04) : 529 - 535
[28] Costimulation of human CD28- T cells by 4-1BB ligand
Bukczynski, J
Wen, T
Watts, TH
EUROPEAN JOURNAL OF IMMUNOLOGY, 2003, 33 (02) : 446 - 454
[29] NOVEL T-CELL ANTIGEN 4-1BB ASSOCIATES WITH THE PROTEIN-TYROSINE KINASE P56(LCK1)
KIM, YJ
POLLOK, KE
ZHOU, Z
SHAW, A
BOHLEN, JB
FRASER, M
KWON, BS
JOURNAL OF IMMUNOLOGY, 1993, 151 (03): : 1255 - 1262
[30] UP-REGULATION OF THE PROTEIN-TYROSINE KINASE P56(LCK) AND CELL-PROLIFERATION BY 4-1BB IN MURINE THYMOCYTES
KIM, YJ
ZHOU, Z
POLLOK, KE
KWON, BS
FASEB JOURNAL, 1994, 8 (04): : A521 - A521

← 1 2 3 4 5 →