Extended Poisson process modelling and analysis of grouped binary data

被引:4
|
作者
Faddy, Malcolm J. [1 ]
Smith, David M. [2 ]
机构
[1] Queensland Univ Technol, Brisbane, Qld 4001, Australia
[2] Thomson Reuters Healthcare USA, Washington, DC 20008 USA
关键词
Binomial distribution; Covariate effects; Dispersion; Poisson process; Precision of estimates; COUNT DATA;
D O I
10.1002/bimj.201100214
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A simple extension of the Poisson process results in binomially distributed counts of events in a time interval. A further extension generalises this to probability distributions under- or over-dispersed relative to the binomial distribution. Substantial levels of under-dispersion are possible with this modelling, but only modest levels of over-dispersion up to Poisson-like variation. Although simple analytical expressions for the moments of these probability distributions are not available, approximate expressions for the mean and variance are derived, and used to re-parameterise the models. The modelling is applied in the analysis of two published data sets, one showing under-dispersion and the other over-dispersion. More appropriate assessment of the precision of estimated parameters and reliable model checking diagnostics follow from this more general modelling of these data sets.
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页码:426 / 435
页数:10
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