SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL 2-HYDROXY-N-(2-TRIFLUOROMETHYL-PHENYL)-BENZAMIDE DERIVATIVES

In order to obtain biological active compounds, the synthesis of some new derivatives with o-hidroxibenzamidic structure was achieved, Starting from 2-hydroxy-N-(2-trifluoromethyl-phenyl)-benzamide and ethyl alpha-halogenated acid esters were obtained ethyl esters, which were condensated with hydrazine giving hydrazides. In reaction between hydrazides and chloro-substituted benzaldehydes were obtained hydrazones. All new synthesized compounds were characterized by physico-chemical methods (FTIR, H-1-NMR, C-13-NMR, MS), which confirmed their Structures.