SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL 2-HYDROXY-N-(2-TRIFLUOROMETHYL-PHENYL)-BENZAMIDE DERIVATIVES

被引:0
|
作者
Ienascu, Ioana M. C. [1 ]
Lupea, Alfa X. [1 ]
Popescu, Iuliana M. [2 ]
Mosoarca, Cristina [3 ]
Zamfir, Alina D. [3 ,4 ]
机构
[1] Polytech Univ, Fac Ind Chem & Environm Engn, Dept Organ Chem, Timisoara 300006, Romania
[2] Banats Agr Sci Univ, Fac Agr, Dept Chem & Biochem, Timisoara 300645, Romania
[3] Natl Inst Res & Dev Electrochem & Condensed Matte, Mass Spectrometry Lab, Timisoara 300224, Romania
[4] Aurel Vlaicu Univ Arad, Arad 310130, Romania
关键词
2-hydroxy-N-(2-trifluoromethyl-phenyl)-benzamide derivatives; ethyl esters; hydrazides; hydrazones; salicylanilide-O-substituted;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In order to obtain biological active compounds, the synthesis of some new derivatives with o-hidroxibenzamidic structure was achieved, Starting from 2-hydroxy-N-(2-trifluoromethyl-phenyl)-benzamide and ethyl alpha-halogenated acid esters were obtained ethyl esters, which were condensated with hydrazine giving hydrazides. In reaction between hydrazides and chloro-substituted benzaldehydes were obtained hydrazones. All new synthesized compounds were characterized by physico-chemical methods (FTIR, H-1-NMR, C-13-NMR, MS), which confirmed their Structures.
引用
收藏
页码:273 / +
页数:5
相关论文
共 50 条
  • [1] Synthesis and characterization of some new 2-hydroxy-n-(3-trifluoromethyl-phenyl)-benzamide derivatives
    Ienascu, Ioana M. C.
    Lupea, Alfa X.
    Popescu, Iuliana M.
    Tomas, Stefan Th.
    Zamfir, Alina D.
    REVISTA DE CHIMIE, 2008, 59 (01): : 56 - 59
  • [2] 2-Hydroxy-N-(2-pyridyl)benzamide
    Wang, WH
    You, ZL
    Liu, WS
    Wang, DQ
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O1772 - O1773
  • [3] 2-Hydroxy-N-(2-hydroxyethyl)benzamide
    Betz, Richard
    Gerber, Thomas
    Hosten, Eric
    Schalekamp, Henk
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2117 - U1250
  • [4] 2-hydroxy-N-(2-phenoxyethyl)benzamide
    Tai, Xi-Shi
    Yin, Jie
    Hao, Ming-Yang
    Liang, Zu-Pei
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O1727 - O1728
  • [5] 2-Hydroxy-N-(4-methylphenyl)benzamide
    Raza, Abdul Rauf
    Nisar, Bushra
    Tahir, M. Nawaz
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2253 - U1906
  • [6] 2-Hydroxy-N-(3-nitrophenyl)benzamide
    Raza, Abdul Rauf
    Nisar, Bushra
    Tahir, M. Nawaz
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O2435 - U1358
  • [7] 2-hydroxy-N-(2-pyridylmethyl)benzamide monohydrate
    Wen, Yong-Hong
    Yu, e-Qin Yu
    Zhang, Kun
    Li, Xue-Mei
    Zhang, Shu-Sheng
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O3782 - O3783
  • [8] Novel N-(2-bromo-phenyl)-2-hydroxy-benzamide Derivatives with Antifugal Activity
    Ienascu, Ioana Maria Carmen
    Balaes, Tiberius
    Petre, Cristiana Virginia
    Pop, Raluca Oana
    Cata, Adina
    Stefanut, Mariana Nela
    Albu, Paul
    Poenaru, Marioara
    REVISTA DE CHIMIE, 2018, 69 (07): : 1876 - 1880
  • [9] SYNTHESIS AND CHARACTERIZATION OF SOME NEW 5-BROMO-2-HYDROXY-BENZAMIDE DERIVATIVES
    Ienascu, Ioana M. C.
    Popescu, Iuliana M.
    Stefanut, Mariana N.
    Cata, Adina
    Tanasie, Cristian
    Balcu, Ionel
    REVUE ROUMAINE DE CHIMIE, 2015, 60 (5-6) : 615 - 618
  • [10] Crystal structures of 3-fluoro-N-[2-(trifluoromethyl)phenyl]benzamide, 3-bromo-N-[2-(trifluoromethyl)phenyl]benzamide and 3-iodo-N-[2-(trifluoromethyl)phenyl]benzamide
    Suchetan, P. A.
    Suresha, E.
    Naveen, S.
    Lokanath, N. K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2016, 72 : 819 - +