Molecular magnetic resonance imaging in cancer

被引:65
|
作者
Haris, Mohammad [1 ]
Yadav, Santosh K. [1 ]
Rizwan, Arshi [2 ]
Singh, Anup [3 ]
Wang, Ena [1 ]
Hariharan, Hari [4 ]
Reddy, Ravinder [4 ]
Marincola, Francesco M. [1 ]
机构
[1] Sidra Med & Res Ctr, Doha 26999, Qatar
[2] All India Inst Med Sci, New Delhi, India
[3] Indian Inst Technol, Ctr Biomed Engn, Delhi, India
[4] Univ Penn, Dept Radiol, Ctr Magnet Resonance & Opt Imaging, Philadelphia, PA 19104 USA
来源
关键词
Cancer; Magnetic resonance imaging; Magnetic resonance spectroscopy; Hyperpolarization; Chemical exchange saturation transfer (CEST) imaging; Reporter genes; Cancer immunotherapy; PROTON MR SPECTROSCOPY; CHOLINE PHOSPHOLIPID-METABOLISM; HUMAN BREAST-CANCER; DECOUPLED P-31 MRS; HUMAN BRAIN-TUMORS; IN-VIVO; PROSTATE-CANCER; COLORECTAL-CANCER; GENE-EXPRESSION; LUNG-CANCER;
D O I
10.1186/s12967-015-0659-x
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.
引用
收藏
页数:16
相关论文
共 50 条
  • [31] Nanoplatforms for magnetic resonance imaging of cancer
    Cywinska, Monika A.
    Grudzinski, Ireneusz P.
    Cieszanowski, Andrzej
    Bystrzejewski, Michal
    Poplawska, Magdalena
    POLISH JOURNAL OF RADIOLOGY, 2011, 76 (02) : 28 - 36
  • [32] Magnetic Resonance Imaging of Rectal Cancer
    Dewhurst, Catherine E.
    Mortele, Koenraad J.
    RADIOLOGIC CLINICS OF NORTH AMERICA, 2013, 51 (01) : 121 - +
  • [33] Magnetic resonance imaging in cervical cancer
    Winter, R
    Ebner, F
    Lahousen, M
    Haas, J
    GYNAKOLOGE, 1996, 29 (03): : 207 - 212
  • [34] Magnetic resonance imaging of the breast cancer
    Seki, T
    Masuda, Y
    Hachiya, J
    Fukushima, H
    Uchigasaki, S
    XXX WORLD CONGRESS OF THE INTERNATIONAL COLLEGE OF SURGEONS, VOLS 1-2, 1996, : 1485 - 1488
  • [35] Magnetic resonance imaging of anal cancer
    Roach, SC
    Hulse, PA
    Moulding, FJ
    Wilson, R
    Carrington, BM
    CLINICAL RADIOLOGY, 2005, 60 (10) : 1111 - 1119
  • [36] Magnetic resonance imaging in prostate cancer
    Heenan, SD
    PROSTATE CANCER AND PROSTATIC DISEASES, 2004, 7 (04) : 282 - 288
  • [37] Magnetic Resonance Imaging of Rectal Cancer
    Costa-Silva, Luciana
    Brown, Gina
    MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA, 2013, 21 (02) : 385 - +
  • [38] Endometrial cancer: magnetic resonance imaging
    Manfredi, R
    Gui, B
    Maresca, G
    Fanfani, F
    Bonomo, L
    ABDOMINAL IMAGING, 2005, 30 (05): : 626 - 636
  • [39] Magnetic resonance imaging for rectal cancer
    Arne Wibe
    Nature Clinical Practice Oncology, 2007, 4 : 222 - 223
  • [40] Magnetic resonance imaging in breast cancer
    Van Goethem, M.
    Tjalma, W.
    Schelfout, K.
    Verslegers, I.
    Biltjes, I.
    Parizel, P.
    EJSO, 2006, 32 (09): : 901 - 910