Current and future therapeutical approaches for COVID-19

被引：15

作者：

Duan, Yongtao ^{[1
]}

Yao, Yongfang ^{[2
]}

Kumar, Senthil Arun ^{[3
]}

Zhu, Hai-Liang ^{[1
,4
]}

Chang, Junbiao ^{[2
]}

机构：

[1] Zhengzhou Univ, Henan Prov Key Lab Childrens Genet & Metab Dis, Childrens Hosp, Zhengzhou 450001, Peoples R China

[2] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Henan, Peoples R China

[3] Zhengzhou Univ, Dept Endocrinol & Metab, Genet, Childrens Hosp, Zhengzhou 450001, Peoples R China

[4] Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China

来源：

DRUG DISCOVERY TODAY | 2020年 / 25卷 / 08期

基金：

中国国家自然科学基金;

关键词：

DRUG DISCOVERY; SARS; PNEUMONIA; PLASMA; ARBIDOL;

D O I：

10.1016/j.drudis.2020.06.018

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Coronavirus 2019 (COVID-19), the WHO-classified novel coronavirus of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly become a global pandemic. To tackle both its spread and virulence, research is ongoing worldwide to develop an effective anti-COVID-19 drug or vaccine. In this review, we explore the clinical understanding and severity of COVID-19 emergence across the world, with a focus on China. We also discuss potential therapeutic targets, either host virus based, that could be used to tackle the COVID-19 outbreak.

引用

页码：1545 / 1552

页数：8

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