Mucositis is a known complication following use of chemotherapy, but fatal mucositis is unusual and management of such cases may be challenging. Pathologically there is denudation of mucosa of gastrointestinal tract. Severe cases can develop ileus and even perforation of bowel wall. We report here a case of multiple myeloma who developed World Health Organization grade 4 gut mucositis following the use of high dose melphalan with the expulsion of "intestine-like" material. (C) 2013 Baishideng. All rights reserved.
机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Div Hematol Malignancies, Med Weill Cornell Med Coll, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Dept Med, Div Hematol Malignancies, Med Weill Cornell Med Coll, 1275 York Ave, New York, NY 10021 USA