Two New Tropane Alkaloids from the Bark of Erythroxylum vacciniifolium Mart. (Erythroxylaceae)

被引:0
|
作者
Queiroz, Emerson F. [1 ]
Zanolari, Boris [2 ]
Marston, Andrew [2 ]
Guilet, David [3 ]
Burgener, Leila [2 ]
Paulo, Marcal de Queiroz [4 ]
Hostettmann, Kurt [2 ]
机构
[1] Ache Labs Farmaceut SA Rodovia, Dept Res & Dev, BR-07034904 Guarulhos, SP, Brazil
[2] Univ Lausanne, Univ Geneva, Sch Pharmaceut Sci, Lab Pharmacognosy & Phytochem, CH-1211 Geneva 4, Switzerland
[3] Univ Angers, Lab SONAS, IFR QUASAV, UFR Sci Pharmaceut & Ingn Sante, F-49100 Angers, France
[4] Univ Fed Paraiba, Lab Quim Prod Nat, BR-58000 Joao Pessoa, Paraiba, Brazil
关键词
Catuaba; aphrodisiac; Erythroxylum vacciniifolium; tropane alkaloids; STEM-BARK; CATUABINE;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new tropane alkaloid N-oxides substituted by a methylpyrrole moiety were isolated from the bark of Erythroxylum vacciniifolium Mart. (Erythroxylaceae), a Brazilian indigenous plant, locally known as catuaba and used in traditional medicine as an aphrodisiac. The alkaloid structures were determined by a combination of high resolution mass spectrometry and multi-dimensional NMR spectroscopy.
引用
收藏
页码:1337 / 1340
页数:4
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