Mapatumumab, A TRAIL Receptor 1 Agonist Antibody, Induces Apoptosis in Bortezomib Resistant Multiple Myeloma.

被引:0
|
作者
Ghoshal, Pushpankur [1 ]
Chitta, Kasyapa [1 ]
Vujcic, Slavoljub [1 ]
Gaddy, Jacquelyne [1 ]
Miles, Kiersten M. [1 ]
Stein, Leighton [1 ]
Sher, Taimur [1 ]
Lee, Kelvin P. [1 ]
Chanan-Khan, Asher A. [1 ]
机构
[1] Roswell Pk Canc Inst, Buffalo, NY 14263 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1106 / 1107
页数:2
相关论文
共 50 条
  • [31] Valproic acid inihibts histone deacetylases and proliferation and induces cell cycle arrest and apoptosis in multiple myeloma.
    Kaiser, M
    Heider, U
    Zavrski, I
    Sterz, J
    Possinger, K
    Sezer, O
    BLOOD, 2005, 106 (11) : 374B - 374B
  • [32] PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL
    Ueno, S.
    Tatetsu, H.
    Hata, H.
    Iino, T.
    Niiro, H.
    Akashi, K.
    Tenen, D. G.
    Mitsuya, H.
    Okuno, Y.
    ONCOGENE, 2009, 28 (46) : 4116 - 4125
  • [33] PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL
    S Ueno
    H Tatetsu
    H Hata
    T Iino
    H Niiro
    K Akashi
    D G Tenen
    H Mitsuya
    Y Okuno
    Oncogene, 2009, 28 : 4116 - 4125
  • [34] Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells
    Yao, Yao
    Sun, Yueyue
    Shi, Min
    Xia, Dandan
    Zhao, Kai
    Zeng, Lingyu
    Yao, Ruosi
    Zhang, Ying
    Li, Zhenyu
    Niu, Mingshan
    Xu, Kailin
    ONCOTARGET, 2016, 7 (45) : 73497 - 73508
  • [35] Evaluation of chimeric anti-TNF monoclonal antibody (infliximab) in refractory (resistant and relapsing) multiple myeloma.
    Langerak, A
    Briggs, A
    Lam, K
    McCloskey, R
    Salmon, S
    BLOOD, 1999, 94 (10) : 312B - 312B
  • [36] JaponiconeA induces apoptosis of bortezomib-sensitive and-resistant myeloma cells in vitro and in vivo by targeting IKKβ
    Zilu Zhang
    Chenjing Ye
    Jia Liu
    Wenbin Xu
    Chao Wu
    Qing Yu
    Xiaoguang Xu
    Xinyi Zeng
    Huizi Jin
    Yingli Wu
    Hua Yan
    Cancer Biology & Medicine, 2022, (05) : 651 - 668
  • [37] A randomized phase II trial of mapatumumab, a TRAIL-R1 agonist monoclonal antibody, in combination with carboplatin and paclitaxel in patients with advanced NSCLC
    Von Pawel, J.
    Harvey, J. H.
    Spigel, D. R.
    Dediu, M.
    Reck, M.
    Cebotaru, C. L.
    Kumm, E.
    Gallant, G.
    Fox, N.
    Camidge, D. R.
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (18)
  • [38] Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types
    Kaplan-Lefko, Paula J.
    Graves, Jonathan D.
    Zoog, Stephen J.
    Pan, Yang
    Wall, Jason
    Branstetter, Daniel G.
    Moriguchi, Jodi
    Coxon, Angela
    Huard, Justin N.
    Xu, Ren
    Peach, Matthew L.
    Juan, Gloria
    Kaufman, Stephen
    Chen, Qing
    Bianchi, Allison
    Kordich, Jennifer J.
    Ma, Mark
    Foltz, Ian N.
    Gliniak, Brian C.
    CANCER BIOLOGY & THERAPY, 2010, 9 (08) : 618 - 631
  • [39] Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib-sensitive and -resistant multiple myeloma cells
    Nishimura, Nao
    Radwan, Mohamed O.
    Amano, Masayuki
    Endo, Shinya
    Fujii, Eri
    Hayashi, Hironori
    Ueno, Shikiko
    Ueno, Niina
    Tatetsu, Hiro
    Hata, Hiroyuki
    Okamoto, Yoshinari
    Otsuka, Masami
    Mitsuya, Hiroaki
    Matsuoka, Masao
    Okuno, Yutaka
    CANCER SCIENCE, 2019, 110 (10) : 3275 - 3287
  • [40] Upregulated expression and function of theα4β1 integrin in multiple myeloma cells resistant to bortezomib
    Sevilla-Movilla, Silvia
    Arellano-Sanchez, Nohemi
    Martinez-Moreno, Monica
    Gajate, Consuelo
    Sanchez-Vencells, Anna
    Valcarcel, Luis V.
    Agirre, Xabier
    Valeri, Antonio
    Martinez-Lopez, Joaquin
    Prosper, Felipe
    Mollinedo, Faustino
    Teixido, Joaquin
    JOURNAL OF PATHOLOGY, 2020, 252 (01): : 29 - 40