Biofabrication of Biopolymer and Biocomposite Scaffolds for Bone Tissue Engineering

被引:1
|
作者
Chen, Yo-Yu
Li, Hui-Lin
Chen, Chang-Cheng
Jiang, Cho-Pei
机构
关键词
Hydroxyapatite; Deposition; Poly(ethylene glycol) (PEG); Poly(epsilon-Caprolactone); Scaffold; FABRICATION;
D O I
10.4028/www.scientific.net/KEM.523-524.374
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The aims of this study were to fabricate biopolymer and biocomposite scaffolds for bone tissue engineering by an air pressure-aided deposition system. A thermosensitive mPEG-PCL-mPEG triblock copolymer was synthesized as a biopolymer material. Biocomposite material was composed of synthesized biopolymer and hydroxyapatite (HA) with a mean diameter of 100 mu m. The weight ratio of HA added to the synthesized biopolymer was 0.5. The experimental results show that the average compressive strength of biocomposite scaffolds with mean pore size of 410 mu m (porosity 81%) is 18.38 MPa which is two times stronger than that of biopolymer scaffolds.
引用
收藏
页码:374 / 379
页数:6
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